OVARIAN FIBROMA TUMORS: A CASE REPORT AND LITTERATURE REVIEW

Thanh Đức Lê1,, Thị Lý Linh Nguyễn2
1 National Cancer Hospital
2 Hanoi Medical University

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Abstract

Meigs syndrome is a rare neoplastic disease characterized by the triad of benign solid ovarian tumor, ascites, and pleural effusion. In postmenopausal women with pleural effusions, ascites, elevated CA-125 level, and pelvic masses, the probability of disseminated disease is high. Nevertheless, the final diagnosis is based on its histopathologic features following surgical removal of a mass lesion. Here we present a case of 56 years old patient who was admitted due to a pelvic mass, pleural effusion, ascites, and elevated serum CA125. Patient was performed unilateral salpingo-oophorectomy, and the postoperative pathology showed fibroma of the ovary.

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References

1. Chi, Dennis S;Berchuck, Andrew; Dizon, Don S; Yashar, Catheryn M. Principle and practice of gynecologic oncology. Seventh ed; Wolters Kluwer; 2017; 1438-1486.
2. Hou YY, Peng L, Zhou M. Meigs syndrome with pleural effusion as initial manifestation: A case report. World J Clin Cases. 2021 Jul 26; 9(21): 5972-5979
3. Meigh JV, Cass JW. Fibroma of the ovary with ascites and hydrothorax: With a report of seven cases. Am J Obstet Gynecol 1937; 33: 249–67.
4. Rhoads JE, Terrell AW. Ovarian fibroma with ascites and hydrothorax (Meigs syndrome): a case. JAMA 1937; 109: 1684
5. Sivanesaratnam V, Dutta R, Jayalakshmi P. Ovarian fibroma--clinical and histopathological characteristics. Int J Gynaecol Obstet. 1990 Nov;33(3):243-7. doi: 10.1016/0020-7292(90) 90009-a. PMID: 1977643.
6. Sung H, Ferlay J, Siegel RL, et al. Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA Cancer J Clin.2021; 71:209.
7. Topalak O, Saygili U, Soyturk M, Karaca N, Batur Y, Uslu T, Erten O. Serum, pleural effusion, and ascites CA-125 levels in ovarian cancer and nonovarian benign and malignant diseases: a comparative study. Gynecol Oncol. 2002 Apr; 85(1):108-13.