LEVELS OF SERUM ZINC, COPPER IN CHRONIC SPONTANEOUS URTICARIA AND RELATIONSHIP DEGREE OF THE DISEASE
Main Article Content
Abstract
Objectives: to determine levels of serum zinc, copper of patients with chronic spontaneous uriticaria and their relationship degree of the disease. Subjects and methods: A cross sectional study uses observation to compare and contrast, including 2 groups: study group 75 patients with chronic spontaneous urticaria, 36 heathy people in the control group at National hospital of dermatology and verneology. Results: Concentation of serum zinc is lower for chronic spontaneous urticaria patients than for healthy people, p< 0,05. However, no relationship of serum zinc, copper with age group, lever disease in chronic spontaneous urticaria. Conclusion: There was a reduction in concentration of serum zinc with chronic spontaneous.
Article Details
Keywords
copper concentration, zinc concentration, chronic spontaneous uritacaria
References
2. Chasapis CT, Loutsidou AC, Spiliopoulou CA, Stefanidou ME. Zinc and human health: an update. Arch Toxicol. 2012;86(4):521-534. doi:10.1007/s00204-011-0775-1
3. Matushevskaya EV, Vladimirova EV, Svirshchevskaya E. Atopic dermatitis and the role of zinc in maintaining skin barrier properties. Klinicheskaya dermatologiya i venerologiya. 2020; 19:297. doi:10.17116/klinderma202019031297
4. Lella ED, Dell’Anna ML, Buttari B, Cristaudo A. Ruolo dello zinco nella modulazione della risposta immune nella dermatite da contatto da nichel. Annali Italiani di Dermatologia Allergologica Clinica e Sperimentale. 2003;57(2-3):82-87.
5. Bonaventura P, Benedetti G, Albarède F, Miossec P. Zinc and its role in immunity and inflammation. Autoimmun Rev. 2015;14(4):277-285. doi:10.1016/j.autrev.2014.11.008
6. Lapi F, Cassano N, Pegoraro V, et al. Epidemiology of chronic spontaneous urticaria: results from a nationwide, population-based study in Italy. Br J Dermatol. 2016;174(5):996-1004. doi:10.1111/bjd.14470