ĐÁNH GIÁ KẾT QUẢ NONG BÓNG PHỦ THUỐC TRONG ĐIỀU TRỊ BỆNH ĐỘNG MẠCH CHI TẦNG DƯỚI GỐI

Abstract

Background: In recent years, with the development of interventional devices and technologies, endovascular intervention with low invasion, low complication has had a predominant role in treatment for infrapopliteal artery diseases. Drug-eluting balloon (DEB) method may reduce restenosis and reintervention rates compared with percutaneous transluminal angioplasty. Objective: To determine the initial and short-term results of the DEB method of treatment for infrapopliteal artery diseases. Method: Patients with symptomatic infrapopliteal artery diseases undergo endovascular intervention by the DEB method at Vietnam National Heart Institute and Dong Do Hospital from January 2019 to March 2022. Treatment result is evaluated after 6-month follow up period. Results: A total of 82 limbs of 74 patients (male: 52.7%, mean age: 73.2 ± 10.8) undergone endovascular intervention by the DEB: 92.7% had chronic limb-threatening ischemia (Rutherford ratio 4, 5, 6 were 26.8%, 61.0%, 4.9%, respectively). Majority of lesions belong to TASC C and D (97.5%). The technical success was 93.9%. The ankle-brachial index before and after the intervention were 0.64 and 0.85, respectively (p < 0.05). The complication rate was 11%, almost cases were minor complications which not affect length of stay in hospital. After 6-month follow-up: restenosis rate was 64.5%, target lesion revascularization rate was 6.1%, major amputation rate was 4.9%, mortality rate was 9.5%. There was an improvement in pain relief and wound healing between before and after the intervention (p < 0.05). Conclusion: The DEB is a safe and effective procedure in treament for infrapopliteal artery diseases. However, we need bigger sample size and more study for confirmation.