Article Sidebar

PDF
Date Published: 17/02/2023
Abstract Views: 175
Views PDF: 142
DOI: https://doi.org/10.51298/vmj.v520i2.4129
Issue
Vol. 520 No. 2 (2022)
Section
Các bài báo
How to Cite
Trịnh, Đức H., & Kim , V. V. . (2023). EVALUATING THE INITIAL SURGICAL TREATMENT OUTCOMES IN MIDDLE-THIRD RECTAL CANCER PATIENT WITH PREOPERATIVE CHEMOTHERAPY AND RADIOTHERAY AT K HOSPITAL. Vietnam Medical Journal, 520(2). https://doi.org/10.51298/vmj.v520i2.4129

EVALUATING THE INITIAL SURGICAL TREATMENT OUTCOMES IN MIDDLE-THIRD RECTAL CANCER PATIENT WITH PREOPERATIVE CHEMOTHERAPY AND RADIOTHERAY AT K HOSPITAL

Đức Hoàng Trịnh1,, Văn Vụ Kim 2,3
1 Hanoi Medical University
2 Hanoi medical university
3 National Cancer Hospital

Main Article Content

Abstract

Objective: Evaluate the initial results of surgical treatment in middle-third rectal cancer patient with preoperative chemotherapy and radiotherapy at K Hospital. Patients and methods: A cross-sectional study on 76 middle-third rectal cancer patients who underwent resection and preoperative chemotherapy combined with radiotherapy at K Hospital between 2019 and 2021. Results: The mean age was 59,7 ± 12,6 years old. Ratio male: female = 1,7: 1. The preoperative chemotherapy and radiotherapy response rate was 98,7%. All patients underwent open anterior resection. Mean duration of operation was 130 ± 18,1 minutes. Median number of lymph node dissected was 11,5 ± 6,9. Median of postoperative hospital stay was 8,3 ± 1,8 days. Anastomosis site leakage was in 1 patient (1,3%). 6 patients (7,9%) had urinary retention and 6 patients (7,9%) experienced infection. There were no intraoperative complication and mortalities. Conclusion: Surgical treatment in middle-third rectal cancer patients with preoperative chemotherapy and radiotherapy was safe with low intraoperative and postoperative complications.

Article Details

Keywords

middle-third rectal cancer, preoperative chemotherapy and radiotheraoy

References

1. Glynne-Jones, R., Wyrwicz, L., Tiret, E., Brown, G., Rödel, C., Cervantes, A., &Arnold, D (2017). Rectal cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow - up. Annals of Oncology, 28, iv22-iv40.
2. Nguyễn Văn Huy (2020). Đánh giá kết quả hóa xạ trị tiền phẫu trong ung thư trực tràng giai đoạn T3-T4/N0. Luận văn thạc sỹ y học, Trường Đại học Y Hà Nội.
3. Phạm Cẩm Phương (2013). Đánh giá hiệu quả của xạ trị kết hợp capecitabine trước mổ trong ung thư trực tràng thấp tiến triển tại chỗ, Luận án tiến sỹ Y học, Trường Đại học Y Hà Nội. .
4. Phạm Văn Bình, Hồ Sĩ Thuyết. Đánh giá đặc điểm kỹ thuật và kết quả sớm phẫu thuật cắt đoạn trực tràng nối máy trong điều trị ung thư trực tràng. VMJ. 2017;545(1).
5. Nguyễn Hoàng Bắc, Nguyễn Hữu Thịnh, Nguyễn Quốc Thái (2010),"Tai biến và biến chứng phẫu thuật nội soi căt nối máy điều trị ung thư trực tràng", Y học T.P. Hồ Chí Minh. 14(1), tr. 119 – 123.
6. Kawahara H., Watanabe K., Ushigome T. và CS (2010), "Retrograde single stapling technique for laparoscopic ultralow anterior resection", Digestive surgery. 27(4), pp. 261-264.
7. Rajput A., Romanus D. (2010), "Meeting the 12 lymph node (LN) benchmark in colon cancer", J Surg Oncol 102, pp. 3.
8. Landi F., Vallribera F., Rivera J.P., et al. (2016), "Morbidity after laparoscopic and open rectal cancer surgery: a comparative analysis of morbidity in octogenarians and younger patients", Colorectal Dis, 18(5), pp. 459-467.
9. Eriksen M. T., Wibe A., Norstein J., Haffner J., Wiig J. N. (2005),"Anastomotic leakage following routine mesorectal excision for rectal cancer in a national cohort of patients", Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland. 7(1), pp.51-7
10. Lange MM, Maas CP, Marijnen C a. M, et al. Urinary dysfunction after rectal cancer treatment is mainly caused by surgery. Br J Surg. 2008;95(8):1020-1028. doi:10.1002/bjs.6126