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Date Published: 20/07/2021
Abstract Views: 282
Views PDF: 183
DOI: https://doi.org/10.51298/vmj.v501i1.414
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Vol. 501 No. 1 (2021)
Section
Các bài báo
How to Cite
Thị Thái Hoà, N. . (2021). KRAS MUTATION CHARACTERISTICS IN SMALL CELLULAR NON-ACCOUNT CANCER AT K HOSPITAL. Vietnam Medical Journal, 501(1). https://doi.org/10.51298/vmj.v501i1.414

KRAS MUTATION CHARACTERISTICS IN SMALL CELLULAR NON-ACCOUNT CANCER AT K HOSPITAL

Nguyễn Thị Thái Hoà

Main Article Content

Abstract

Objective: To evaluate the KRAS mutation in non-small cell lung cancer patients at K hospital. Objects and methods: Retrospective description of 931 NGS test samples, including 758 tissue samples from non-small cell lung cancer patients at K Hospital from 1/2019. The test is done at HCMCT Genetics Institute using Massively parallel DNA by next generation sequencing technology. Results: KRAS mutation accounted for 20.1%; mainly occurs in men, accounting for 92%. 9% of the KRAS mutation occurs concurrently with another mutation (EGFR, ALK, BRAF, MET. PI3KCA). Mutations in Codon 12 accounted for 81.3%; codon 13 accounts for 18.7%. Conclusion: The KRAS mutation in the K hospital survey is consistent with the data in the literature

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Keywords

Non-small cell Lung cancer, KRAS mutation

References

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