APPLY MOISTURE ABSORPTION ABILITY OF AEROSIL IN THE PREPARATION OF HIGH-CONTENT KIM TIEN THAO EXTRACT FILM-COATED TABLETS

Nguyễn Đăng Thoại, Khưu Mỹ Lệ, Nguyễn Mạnh Huy

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Abstract

Objectives: Making high-content kim tien thao extract’ tablets to reduce the number of pills in one drink, helping medicine more convenient. Materials and methods: Kim tien thao medicinal herbs were extracted by hot water.Granulation method was used to prepare film-coated tablets. The composition of tablets includes kim tien thao extract, Avicel, starch, aerosil in different proportions. Evaluate the quality of tablets according to the method and quality criteria in the Vietnamese Pharmacopoeia V. Results:The amount of kim tien thao extracted in one tablet is 200 mg (compared to 120 mg of tablet on market) and the amount of aerosil is 0,4%. Kim tien thao tablets meet the requirements on quality of tablets described in Vietnamese pharmacopoeia V. Conclusions: High-contentkim tien thao extract’ tabletswere prepared and met the quality requirements of tablets. It could be used in treatment with the effects of diuretic and increasing uric acid secretion.

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