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Date Published: 17/02/2023
Abstract Views: 600
Views PDF: 181
DOI: https://doi.org/10.51298/vmj.v520i2.4162
Issue
Vol. 520 No. 2 (2022)
Section
Các bài báo
How to Cite
Nguyễn, B. K., Nguyễn, T. T. H., Đinh, T. T. H., Đào, B. N., & Nguyễn, M. H. (2023). LEFT ATRIAL FUNCTION ON SPECKLE TRACKING ECHOCARDIOGRAPHY IN PATIENTS WITH HEART FAILURE WITH REDUCED EJECTION FRACTION. Vietnam Medical Journal, 520(2). https://doi.org/10.51298/vmj.v520i2.4162

LEFT ATRIAL FUNCTION ON SPECKLE TRACKING ECHOCARDIOGRAPHY IN PATIENTS WITH HEART FAILURE WITH REDUCED EJECTION FRACTION

Bảo Khánh Nguyễn1,2,, Thị Thu Hoài Nguyễn2, Thị Thu Hương Đinh2,3, Bích Ngọc Đào2, Mạnh Hùng Nguyễn2,3
1 Hospital of post and telecommunications
2 Bach Mai hospital
3 Hanoi medical university

Main Article Content

Abstract

Objectives: This study aims to investigate left atrial peak strain using speckle tracking echocardiography in patients with heart failure with reduced ejection fraction. Methods: Patients with chronic heart failure with reduced ejection fraction (EF ≤ 40%) without significant valvular heart disease and congenital heart disease and a control group including and age and sex matched healthy subjects were enrolled in the study. Echocardiographic Cardiac function quantification was performed in all subjects using echocardiography. Left atrial peak strain was measured by speckle tracking echocardiography on apical four-chamber view and apical two-chamber view. Results: From 02/2022 to 7/2022, 188 subjects were recruited in the study including 126 patients with heart failure with reduced ejection fraction; male 78.6%, female 21.4%; mean age 59,3 ± 16,4 and a control group consisted of 62 healthy subjects. In patients with heart failure with reduced ejection fraction, 38.1% had coronary artery disease, 31.3% had hypertension, 9.5% had diabetes. Left atrial peak strain on apical four-chamber view and apical two-chamber view were 17.7 ± 7,5% and 15.5 ± 7,1%, respectively, significantly lower than left atrial peak strain of healthy subjects. Patients with left ventricular hypertrophy had lower left atrial peak strain compared to patients without left ventricular hypertrophy (p<0,05). Patients with dilated left ventricular had lower left atrial peak strain compared to patients without dilated left ventricular (p<0,05). Patients with moderate mitral regurgitation had the lowest left atrial peak strain compared to patients with mild mitral regurgitation and patients without mitral regurgitation (p<0,05). Patients with systolic pulmonary artery hypertension had lower left atrial peak strain compared to patients without systolic pulmonary artery hypertension (p<0,05). Conclusions: Patients with heart failure and reduced ejection fraction had significantly lower left atrial peak strain compared to their age and sex matched healthy subjects. Left atrial peak strain in heart failure and reduced ejection fraction were in relation to left ventricular hypertrophy and dilation, to mitral regurgitation and to systolic pulmonary artery hypertension.

Article Details

Keywords

Heart failure with reduced ejection fraction, left atrial strain, left atrial function

References

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