DỊCH TỄ HỌC LÂM SÀNG, CẬN LÂM SÀNG Ở TRẺ EM BỊ BỆNH BASEDOW TẠI BỆNH VIỆN ĐA KHOA XANH PÔN HÀ NỘI

Abstract

Hyperthyroidism is a medical condition caused by an increase in thyroid hormone in the blood, of which 95% is caused by Basedow’s disease, a disease that damages many organs: cardiology, nerves, eyes,... affecting the quality of children’s life. Objectives: To describe the clinical and paraclinical features in children with Basedow's disease at Saint Paul General Hospital from 2017 to 2022. Research subjects: 25 children who met the criteria for Basedow’s disease diagnosis were treated at the Pediatrics Department of Saint Paul General Hospital from 2017 to 2022. Methods: Descriptive study of a series of cases. Results: Girls were more affected than boys with a ratio of 4:1, 76% in the 10-15-year-old group, 20% in the 5-9-year-old group, 4% in the < 5-year-old group. The average time from illness onset to diagnosis was 3.8 ± 2.4 months. The common symptoms: fatigue 92%, hot and humid skin, excessive sweating (92%), insomnia (88%), weight loss (72%), hand tremors (64%), emotional changes (60%), menstrual disorders (8%) and delayed puberty (8%). Physical development disorders: 84% normal , 12% thinness, 4% overweight. 60% bulging eyes. 100% goiter; grade I:II:III was 24%:72%:4%. 100% blood TSH concentration was very low and not measured, FT4 concentration was elevated (46.7 ± 19.3 pmol/L), T3 concentration was elevated (7.7 ± 7.5 nmol/L), 100% TRAb increased (16.1 ± 10.4 IU/L). 100% ultrasound thyroid gland increase in size, electrocardiogram: 100% of children had tachycardia, echocardiography: 8% of children had heart valve regurgitation. Conclusion: Basedow's disease greatly affects the physical development, neuro-mental and genital disorders in children, the late diagnosis rate is still high, it is necessary to diagnose early and treat promptly to avoid complications and fully develop the children.