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CORRELATION BETWEEN THE FRACTION OF EXHALED NITRIC OXIDE LEVEL WITH SOME CLINICAL, LABORATORY AND LEVELS OFF ASTHMA CONTROL IN ADULT PATIENTS
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Abstract
Background: Asthma is a common respiratory disease in adults that is increasing in the world as well as in Vietnam. The fraction of exhaled nitric oxide (FeNO) level is considered a pointing marker in asthma. Many studies have shown that FeNO can be used to support to diagnosis and control of asthma in adults. However, it is not clear whether FeNO correlates with the clinical, laboratory, and level of asthma control of patients. Methods: A cross-sectional descriptive study on patients who came for examination and management at Chronic Obstructive Pulmonary Disease and Asthma Management Clinic at Bach Mai hospital from October 2021 to June 2022. Result: 109 adult asthmatic patients aged from 22 to 85 years old (mean 56 years old) participated in the study including 58.7% female and 41.3% male. The mean FeNO level of the patients is 32.15 ± 22.67. The result shows that FeNO doesn’t have a correlation with clinical asthma as well as spirometry. However, it has a positive correlation with the number of eosinophils and a negative correlation with the degree of asthma control. Conclusion: FeNO has an association with the number of eosinophils and asthma control status.
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Keywords
Asthma, Fraction of exhaled nitric oxide, FeNO, asthma control
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