INCIDENCE, CHARACTERISTICS, RISK FACTORS AND EFFECTS OF ACUTE KIDNEY INJURY IN SEVERE AND CRITICAL COVID-19 PATIENTS

Nhuận Thủ Tô1, Thị Ngọc Thảo Phạm2, Minh Khôi Lê2,3,
1 Xuyen A hospital
2 University of Medicine and Pharmacy at Ho Chi Minh City
3 University of Medicine and Pharmacy at Ho Chi Minh City hospital

Main Article Content

Abstract

Objective: This study aimed to describe the characteristics and to determine the incidence, risk factors and effects of acute kidney injury (AKI) in severe and critical COVID-19 patients. Method: We retrospectively studied COVID-19 patients admitted to the COVID-19 Intensive Care Center, University Medical Center Ho Chi Minh City. Results: The study recruited 356 severe and critical COVID-19 patients. The AKI incidence was 59.8%, among which stage 2 of 13.8% and stage 3 of 23.6%. Cytokine score and colistin use were independently related to the occurrence of AKI. The median time of hospital stay was of 15 days. 14.6%, 50.3%, and 17.42% of patients required renal replacement therapy, invasive mechanical ventilation, and blood transfusion, respectively. The overall mortality was 35.96%. The patients with AKI had a longer hospital stay, higher rate of invasive mechanical ventilation, blood transfusion, and mortality. Conclusions: AKI was common in severe and critical COVID-19 patients and associated with increased disease severity, prolonged hospital stay and higher mortality.

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References

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