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THE RESEARCH AND APPLICATION OF DUAL ENERGY COMPUTED TOMOGRAPHY IN THE ASSESSMENT OF LUNG CANCER
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Abstract
Purpose: Study on the value of virtual non contrast images (VNC) of DUAL Energy computed tomography (DECT) in assessment lung cancer. Compare the difference in image image quality of lung cancer lesions on DECT of virtual monochromatic and mixed images. Compare the difference of radiation dose in patient between DECT and Standard Dose Computed (SDCT). Materials and Methods: We conducted a cross sectional descriptive study in 50 patients diagnosed lung cancer with dual energy CT of thoracic venous phases at K Central Hospital from 03/2022-08/2022. Process the Data File into a composite image that corresponds to conventional CT at 66 keV, virtual non contrast and monochromatic images with the energy range from 40 keV to 140 keV. Compare virtual non contrast images with the true non contrast images (TNC) and evaluate the quality of monoenergetic images. Results: The study was composed of 50 patients (40 males, 10 females). The mean age of patients was 57.12±11.92. Contrast noise ratio of lung tumor has the highest value in monochromatic image at 40 keV (2.57±0.37), 60 keV (1.71±0.34) higher than mixed image at 66 keV (0.71±0.41). The subjective assessment comparing the series of monochrome images with the composite images showed the highest image quality score at 60 keV (4.54±0.5) and was not significantly different with mixed image (4.42±0.67) (p=0.135). ). The density of lung tumors of TNC is 42.63±8.83 and VNC images is 43.64±9.55 (p=0.126), the contrast to noise ratio value of TNC is 0.76±0.34 and VNC is 0.71±0.3 (p= 0.14), the image quality score of TNC is 4.48±0.68 and VNC is 4.12±0.63 (p<0.005). The total effective radiation dose for patients with DECT technique was 3.2±0.48 mSv lower than SDCT technique was 7.2±2.03 mSv. Conclusion: Virtual non contrast images can completely replace the role of true non contrast images in lung cancer assessment. The can reduce up to 55.56% effective radiation dose for patinents. In virtual monoenergetic, the 60-80 keV sequence has good image quality, the 60 keV sequence can highlight the lung tumor lesion and the image quality is better than other monoenergetic sequence and the mixed images.
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Keywords
Lung cancer, Dual energy CT, virtual non contrast, virtual monochromatic
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