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Date Published: 17/02/2023
Abstract Views: 328
Views PDF: 164
DOI: https://doi.org/10.51298/vmj.v520i2.4201
Issue
Vol. 520 No. 2 (2022)
Section
Các bài báo
How to Cite
Lê, T. N., Trần, T. C. M., & Trần, T. N. A. . (2023). REFERENCE INTERVALS FOR HEMATOLOGICAL AND HEMOSTATIC PARAMETERS IN HEALTHY PREGNANT WOMEN DURING THE THIRD TRIMESTER. Vietnam Medical Journal, 520(2). https://doi.org/10.51298/vmj.v520i2.4201

REFERENCE INTERVALS FOR HEMATOLOGICAL AND HEMOSTATIC PARAMETERS IN HEALTHY PREGNANT WOMEN DURING THE THIRD TRIMESTER

Thị Nga Lê1, Thị Chi Mai Trần1,2, Thị Ngọc Anh Trần3,
1 Hanoi medical university
2 Vietnam National Children's Hospital.
3 Viet Duc Hospital

Main Article Content

Abstract

The aim of this study was  to establish reference intervals for some hematological and hemostatic parameters in healthy women during the third trimester of pregnancy. A prospective cross-sectional descriptive study method included 142 healthy pregnant women aged from 18 to 35 years with a gestational age of 28-38 weeks, single fetus, negative proteinuria, diastolic blood pressure <90 mmHg; previous pregnancies and deliveries with no history of complications.  Red blood cell (RBC), hemoglobine (Hb), hematocrit (Hct), mean corpuscular volume (MCV), mean corpuscular hemoglobine (MCH), mean corpuscular hemoglobine concentration (MCHC), white blood cell (WBC), platelet count (PLT) were analyzed on the Celldyn Ruby (Abbott). Prothrombin time (PT) (second, INR), activated partial thromboplastin time APTT (second, disease/control ratio), fibrinogen (g/L) were performed on IL top 500 ACL. Reference intervals of thirteen hematological and coagulation indices of pregnant women have been established and are a reference for laboratories and clinicians.

Article Details

Keywords

pregnant women, reference interval, hematology, coagulation, third trimester

References

1. Olukayode Akinlaja, sistant Professor. Department of Obstetrics and Gynecology, University of Tennessee College of Medicine, Chattanooga, Tennessee, USA: Hematological Changes in Pregnancy - The Preparation for Intrapartum Blood Loss. Obstetrics & Gynecology International Journal. 2016;4(3).
2. Anna Klajnbard, Pal B. Szecsi, Nina P. Colov, et al. Laboratory reference intervals during pregnancy, delivery and the early postpartum period. Clin Chem Lab Med. 2010;8(2): 237-248.
3. Yi Jina, Jie Lua, Hong Jin, et al. Reference intervals for biochemical, haemostatic and haematological parameters in healthy Chinese women during early and late pregnancy. Clin Chem Lab Med. 2017.
4. Odhiambo C, Omolo P, Oyaro B, et al. Establishment of reference intervals during normal pregnancy through six months postpartum in western Kenya. Scientific Report. 2017;12(4):
5. Horowitz G.L, Altale S, Ceriotti F et al (2010). Defining, Establishing, and Verifying Reference Intervals in the Clinical Laboratory: Approved Guideline. CLSI document C28-A3, Third edition, Clinical and Laboratory Standards Institute, Wayne.
6. Chen H-M, Kuo F-C, Chen C, et al. New trimester-specific reference intervals for clinical biochemical tests in Taiwanese pregnant women-cohort of TMICS. Scientific Report. 2020; 16(12):15.
7. Abbasi-Ghanavati M, Greer LG, Cunningham FG. Pregnancy and laboratory studies: a reference table for clinicians. Obstet Gynecol. 2009; 114: 1326- 1331.
8. Huỳnh Thị Bích Huyền và cộng sự. Thiết lập khoảng tham chiếu các chỉ số huyết học trên người trưởng thành cho phòng xét nghiệm bệnh viện truyền máu huyết học. Y học Việt Nam. 2018; tập 446-tháng 5-số đặc biệt: 704-715.
9. Nguyễn Anh Trí. Đông máu - ứng dụng trong lâm sàng. Nhà xuất bản y học Hà Nội. 2002.