KẾT QUẢ ĐIỀU TRỊ SỐC NHIỄM KHUẨN TẠI BỆNH VIỆN BỆNH NHIỆT ĐỚI TRUNG ƯƠNG GIAI ĐOẠN 2017 - 2022

Abstract

A cross-sectional study to describe  the outcomes of septic shock of 260 patients who were ≥ 18 years old with diagnosed with septic shock after being hospitalized at National Hospital of Tropical Diseases in 2017-2022. The results shown that, at hospital admission, 98.8% of patients had SOFA score ≥ 2 points (mean 10 ± 4 points); the rate of positive blood culture accounted for 23.5%; more gram (-) than gram (+) bacteria, 16.2% and 7.3% respectively. The most common antibiotics given to patients with septic shock were Imipenem+cilastatin (44.6%), Meropenem (39.6%) and Linezolid (26.9%); 68.1% of patients were given a combination of 2 antibiotics. Nor-epinephrine was the vasopressor of choice in 98.8% of cases, with an average dose of 0.28±0.44 mcg/kg/min; 76.2% of patients received 2 or more vasopressors. Within 6 hours of shock, the proportion of patients with mean blood pressure (MAP) > 65 mmHg and urine ≥ 0.5 ml/kg/hour was 80.8% and 35.0%, respectively. There were 38.1% of cases out of shock; with 14.1% of cases re-shocked occurring on average 12±10 days after escaping septic shock, the recovery rate was 42.9%. Early (≤3 days) and late (>3 days) deaths occurred in 30.4% and 34.6% patients, respectively