OUTCOMES OF RETROPERITONEOSCOPIC ADRENALECTOMY IN CONN’S SYNDROME CAUSED BY ADRENAL ADENOMAS

Việt Tuấn Nguyễn1,, Long Hoàng1, Văn Minh Võ2, Văn Linh Nguyễn2
1 Hanoi medical university
2 GERMANY FRIENDSHIP HOSPITAL

Main Article Content

Abstract

Introduction: Evaluation of the outcomes of retroperitoneoscopic adrenalectomy in Conn’s syndrome caused by adreanal adenomas. Method: We retrospectively reviewed the results of 88 patients with Conn’s syndrome were operated on endoscopically between January 2018 and June 2022 in Viet Duc hospital and Medical University Hospital. The results was assessed by blood test and image after surgery. Result: Mean age was 44,01 ± 11,18 years old, the oldest was 69 years old and the youngest was 24 years old, femal/male ratio is 2,82. 95,4% of patients had clinical hypertension. In term of imaging, 91,3% have hypoechoic images on ultrasound, 89,9% have images with tumor grade ≤ 25 HU on computed tomography. The mean operative time was 58,8 ± 16,7 minutes, the mean postoperative time was 3,9 ± 1,6 days, no patient die and open surgery was 0 %/ 100% of the patients had normal potassium test and no tumor on ultrasound, improved symptoms of hypertension in 86,6% of patients, very satisfied patients after surgery reached 87,8%. Conclusion: Retroperitoneal laparoscopic surgery for treatment of Conn’s syndrome due to adrenal adenoma is a safe surgical method with short postoperative period, high aesthetics and good results in sieving as well as quality of life patients.

Article Details

References

1. Funder JW, Carey RM, Mantero F, et al. The Management of Primary Aldosteronism: Case Detection, Diagnosis, and Treatment: An Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab. 2016;101(5):1889-1916. doi:10.1210/jc.2015-4061
2. Vũ Đức Hợp, Vũ Lê Chuyên. Một Số Nhận Xét về Điều Trị u Tuyến Thượng Thận Tại Bệnh Viện Bình Dân Từ Năm 1992-1999, Y Học Việt Nam. 2001; Tập 4, Số 5, Tr193-195.
3. Madani A, Lee JA. Surgical Approaches to the Adrenal Gland. Surg Clin North Am. 2019; 99(4):773-791. doi:10.1016/j.suc.2019.04.013
4. Walz MK, Gwosdz R, Levin SL, et al. Retroperitoneoscopic adrenalectomy in Conn’s syndrome caused by adrenal adenomas or nodular hyperplasia. World J Surg. 2008; 32(5):847-853. doi:10.1007/s00268-008-9513-0
5. Young WF. Minireview: primary aldosteronism--changing concepts in diagnosis and treatment. Endocrinology. 2003;144(6):2208-2213. doi: 10.1210/en.2003-0279
6. Nghiên cứu đặc điểm hình ảnh và giá trị của cắt lớp vi tính 64 dãy trong chẩn đoán u tuyến thượng thận | Hội Điện Quang và Y Học Hạt Nhân. Accessed October 10, 2022. https://www.radiology.com.vn/bao-cao-khoa-hoc/nghien-cuu-dac-diem-hinh-anh-va-gia-tri-cua-cat-lop-vi-tinh-64-day-trong-chan-doan-u-tuyen-thuong-than-n333.html
7. Tuncel A, Langenhuijsen J, Erkan A, et al. Comparison of synchronous bilateral transperitoneal and posterior retroperitoneal laparoscopic adrenalectomy: results of a multicenter study. Surg Endosc. 2021;35(3):1101-1107. doi:10.1007/s00464-020-07474-y
8. Young WF. Diagnosis and treatment of primary aldosteronism: practical clinical perspectives. J Intern Med. 2019;285(2):126-148. doi: 10.1111/joim.12831