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CLINICAL CHARACTERISTICS, PARACLINICAL FEATURES AND TREATMENT OUTCOME OF REPERFUSION THERAPHY IN YOUNG ADULTS WITH ACUTE ISCHEMIC STROKE
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Abstract
Objectives: Clinical characteristics, paraclinical features and treatment outcome of reperfusion theraphy in young adults (18 -45 years) with acute ischemic stroke at the Stroke Center-Bach Mai hospital. Methods: This study retrospectively reviewed the records of all 18 to 45-year-old patients who were admitted to the Stroke center of Bach Mai hospital from January 2021 to May 2022. Outcome included modified Rankin Scale after 90 days, expanded throbolysis in cerebral infarction score, and symptomatic intracranical hemorrhage. Results: There were 171 patients, male/female ratio was 2,2/1 the average age was 38±5,9 years. Stroke etiologies in young patients included large artery atherosclerosis (32,1%), cardio-embolism (17%), and embolic stroke of undetermined source (31%). In the survey of risk factors, the common risk factors were smoking (24,6%), high blood pressure (23,4%), hyperlipidemia (15%). In our survey, 53,8% of the patients had triglyceride levels above 1.7 mmol/l. There were 33,3% of patients receiving reperfusion therapy. Results of reperfusion therapy: successful reperfusion (expanded throbolysis in cerebral infarction score 2b-3) was achieved in 100%; The symptomomatic intracranial hemorrage rate was 14%; after 90 days, Good functional outcome (modified Rankin Scale 0-2) was achieved in 82,4%; mortality rate was 5,3%. Glasgow score at admission≤ 13, high NIHSS, low ASPECT and posterior circulatory infarction were associated with mortality rate with p<0,05. Conclusions: Our study found that the common risk factors of young adults with acute ischemic stroke were smoking (24,6%), high blood pressure (23,4%), hyperlipidemia. These patients receiving reperfusion therapy at Stroke center-Bach Mai hospital had a good outcome at three months hospital discharge. Glasgow score at admission≤ 13, high NIHSS, low ASPECT and posterior circulatory infarction were associated with mortality rate.
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