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Date Published: 19/02/2023
Abstract Views: 1003
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DOI: https://doi.org/10.51298/vmj.v522i1.4225
Issue
Vol. 522 No. 1 (2023)
Section
Các bài báo
How to Cite
Nguyễn, T. L., Nguyễn, B. V. ., Đinh , T. P. L. ., Nguyễn, V. L. ., & Lê, T. T. L. (2023). HISTOPATHOLOGICAL CHARACTERISTICS OF GASTRIC MUCOSA IN HELICOBACTER PYLORI-POSITIVE DUODENAL ULCER PATIENTS. Vietnam Medical Journal, 522(1). https://doi.org/10.51298/vmj.v522i1.4225

HISTOPATHOLOGICAL CHARACTERISTICS OF GASTRIC MUCOSA IN HELICOBACTER PYLORI-POSITIVE DUODENAL ULCER PATIENTS

Thanh Liêm Nguyễn1,, Bá Vượng Nguyễn2, Thị Phương Liên Đinh 2, Văn Luân Nguyễn1, Thị Thúy Loan Lê1
1 Can Tho University of Medicine - Pharmacy
2 Vietnam Military Medical Academy

Main Article Content

Abstract

Objective: Determination of the rate of histopathological damage of gastric mucosa in duodenal ulcer patients infected with H. pylori. Subjects and methods: The study was carried out at Can Tho University of Medicine and Pharmacy Hospital from January 2015 to December 2016. We performed gastrointestinal endoscopy to diagnose duodenal ulcer, gastric mucosa biopsy for rapid urease test, histopathology for H. pylori bacteria and lesions on histopathology. Results: Histopathology of gastric mucosa in 102 duodenal ulcer patients with H. pylori infection participating in the study. Active chronic inflammation accounted for 87.3%, atrophic inflammation accounted for 56.9% and intestinal metaplasia accounted for 18.6%. There was no association between chronic active inflammation, atrophic inflammation and intestinal metaplasia with gender, age group and H. pylori density. Conclusion: The most common histopathology of gastric mucosa is chronic active inflammation, atrophic inflammation; Intestinal metaplasia is less common. Chronic active inflammation, atrophic inflammation and intestinal metaplasia were not associated with H. pylori density in duodenal ulcer patients with H. pylori infection.

Article Details

Keywords

Duodenal ulcer, Helicobacter pylori, Histopathology.

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