TÌNH TRẠNG DI CĂN HẠCH VÀ MỐI LIÊN QUAN VỚI MỘT SỐ ĐẶC ĐIỂM GIẢI PHẪU BỆNH UNG THƯ BIỂU MÔ DẠ DÀY

Abstract

Objectives: Gastric cancer is popular cancer in the world. Prognosis depends on the histopathological type as well as the stage of metastasis. The study aims to determine the status of lymph node metastasis and its relationship with some histopathological features of gastric carcinoma. Methods: This cross-sectional study included two hundred twenty-two patients with gastric carcinoma whose diagnosed by histopathology of surgical specimens in Tan Trieu Facility - Vietnam National Cancer Hospital. The relationship between lymph node metastasis and histopathological features of gastric carcinoma was determined by a chi-square test with statistical significance p<0,05. Results: In the total of two hundred twenty-two patients, there were 7 subtypes of histopathology. Tubular gastric adenocarcinoma (64.86%) was the most popular subtype, followed by poorly cohesive gastric carcinoma (27.93%). Along with that, 62.16% had lymph node metastasis. N0 (37.84%) was the most stage lymph node metastasis, followed by N2 (19.37%), N3a (18.47%), N1 (17.57%) and N3b (6.76%). There was a covariate relationship between tumor staging, macroscopy features, vessel invasion, and nerve invasion with lymph node metastasis (p<0.05). There was no relationship between subtypes of histopathology, location and size of the tumor with lymph node metastasis (p>0.05). Conclusions: gastric cancer had a high rate of lymph node metastasis. There was a covariate relationship between tumor staging, macroscopy features, vessel invasion, and nerve invasion with lymph node metastasis.