GIANT STROMAL TUMOR OF THE DUODENUM: RARE CLINICAL CASE AND LITERATURE REVIEW

Hoàng Nguyễn1,, Đức Anh Nguyễn1
1 Hanoi medical university hospital

Main Article Content

Abstract

Gastrointestinal stromal tumors -GIST was at first attributed to Cajal's cells, in mesodermal tissue but it has nowadays been recognized that GISTs arise from multipotential mesenchymal stem cells. GISTs typically occur in older adults, and the median patient age in the major series has varied between 60–65 years. GISTs are relatively rare under the age 40 of years. GISTs inn the stomach occur in 60%, 30% in the jejunum or ileum, 5% in the duodenum, 5% in the rectum, and <1% in the esophagus. Duodenal GIST comprises 10%-20% of small-intestinal GISTs. Giant duodenal GIST are rarely. We report a giant duodenal GIST and review of literature.

Article Details

References

1. Joensuu H. Gastrointestinal stromal tumor (GIST). Ann Oncol. 2006 Sep;17 Suppl 10:x280-286.
2. Miettinen M, Lasota J. GASTROINTESTINAL STROMAL TUMORS. Gastroenterol Clin North Am. 2013 Jun;42(2):399–415.
3. Morcos B, Al-Ahmad F. A large gastrointestinal stromal tumor of the duodenum: a case report. J Med Case Reports. 2011 Sep 14;5:457.
4. Miettinen M, Kopczynski J, Makhlouf HR, Sarlomo-Rikala M, Gyorffy H, Burke A, et al. Gastrointestinal stromal tumors, intramural leiomyomas, and leiomyosarcomas in the duodenum: a clinicopathologic, immunohistochemical, and molecular genetic study of 167 cases. Am J Surg Pathol. 2003 May; 27(5):625–41.
5. Tien YW, Chih Yuan L, Huang CC, Hu RH, Lee CM. Surgery for Gastrointestinal Stromal Tumors of the Duodenum. Annals of surgical oncology. 2009 Oct 1;17:109–14.
6. Beham A, Schaefer IM, Cameron S, von Hammerstein K, Füzesi L, Ramadori G, et al. Duodenal GIST: a single center experience. Int J Colorectal Dis. 2013 Apr;28(4):581–90.
7. Goh BKP, Chow PKH, Ong HS, Wong WK. Gastrointestinal stromal tumor involving the second and third portion of the duodenum: treatment by partial duodenectomy and Roux-en-Y duodenojejunostomy. J Surg Oncol. 2005 Sep 15;91(4):273–5.