CLINICAL, RADIOLOGICAL, PATHOLOGICAL, AND DEFECT CHARACTERISTICS OF PATIENTS AFTER OROMANDIBULAR RESECTION DUE TO CANCER

Bình Nguyên Lại1,, Tài Sơn Nguyễn2, Quang Đức Nguyễn2
1 National Hospital of Odonto-Stomatology, Hanoi
2 108 Military Central Hospital

Main Article Content

Abstract

Objective: This paper aims to describe clinical, radiological, pathological, and defect features of patients after composite oromandibular resection due to cancer. Methods: The study was conducted in 63 patients were diagnosed with maxillofacial cancer and had oromandibular resected in Department of Plastic and Aesthetic Surgery, Hanoi National Hospital of Odonto – Stomatology from May 2014 to July 2021. Results: The mean age was 54.05 ± 13.14 years (range, 19-84 years), male/female ratio was 2/1. The mean of time to presentation was 4.44 ± 5.49 months (range, 2 weeks to 30 months). The most common clinical symptoms were tumor (60.3%), ulceration (69.8%), pain (65.1%), bleeding (33.3%), loose teeth (22.2%), and neck nodes (19.0%). Most of tumors were located on lower gum (39.7%), floor of mouth (27.0%) and mandible (17.5%). 96.8% of patients had mandibular invasion on radiological methods. Pathological results showed most of them were squamous cell carcinoma (81.0%). Most of patients were presented with stage IV (74.6%). Conclusion: Symptoms of maxillofacial cancer are easily confused with several benign conditions, so the patients have to be carefully examined and assigned appropriate radiology and laboratory tests to diagnose soon and minimize damage of surrounding structures due to tumor resection.

Article Details

References

1. C. G. Wallace, Y.-M. Chang, C.-Y. Tsai, and F.-C. Wei, “Harnessing the potential of the free fibula osteoseptocutaneous flap in mandible reconstruction,” Plast Reconstr Surg, vol. 125, no. 1, pp. 305–314, Jan. 2010, doi: 10.1097/PRS.0b013e3181c2bb9d.
2. P. Evans, P. Q. Montgomery, and P. J. Gullane, Principles and Practice of Head and Neck Surgery and Oncology, 2nd Edition. CRC Press, 2009.
3. B. P. Kumar, V. Venkatesh, K. A. J. Kumar, B. Y. Yadav, and S. R. Mohan, “Mandibular Reconstruction: Overview,” J. Maxillofac. Oral Surg., vol. 15, no. 4, pp. 425–441, Dec. 2016, doi: 10.1007/s12663-015-0766-5.
4. O. Camuzard et al., “Primary radical ablative surgery and fibula free-flap reconstruction for T4 oral cavity squamous cell carcinoma with mandibular invasion: oncologic and functional results and their predictive factors,” Eur Arch Otorhinolaryngol, vol. 274, no. 1, Art. no. 1, Jan. 2017, doi: 10.1007/s00405-016-4219-7.
5. Hàn Thị Vân Thanh, “Nghiên cứu điều trị ung thư biểu mô khoang miệng có sử dụng kỹ thuật tạo hình bằng vạt rãnh mũi má.” Luận án Tiến sĩ, Trường Đại học Y Hà Nội, 2013.
6. Nguyễn Anh Khôi, “Nghiên cứu tạo hình khuyết hổng sau phẫu thuật tạo hình ung thư hốc miệng bằng vạt da cân cẳng tay quay.” Luận án Tiến sĩ, Đại học Y Dược Thành phố Hồ Chí Minh, 2017.
7. J. M. López-Arcas et al., “The fibula osteomyocutaneous flap for mandible reconstruction: a 15-year experience,” J Oral Maxillofac Surg, vol. 68, no. 10, pp. 2377–2384, Oct. 2010, doi: 10.1016/j.joms.2009.09.027.
8. L. P. Rao, S. R. Das, A. Mathews, B. R. Naik, E. Chacko, and M. Pandey, “Mandibular invasion in oral squamous cell carcinoma: investigation by clinical examination and orthopantomogram,” Int J Oral Maxillofac Surg, vol. 33, no. 5, Art. no. 5, Jul. 2004, doi: 10.1016/j.ijom.2003.10.006.
9. T. A. Zrnc et al., “Complex Mandibular Reconstruction for Head and Neck Squamous Cell Carcinoma-The Ongoing Challenge in Reconstruction and Rehabilitation,” Cancers (Basel), vol. 12, no. 11, Art. no. 11, Oct. 2020, doi: 10.3390/cancers12113198.