TREATMENT OF NON-INVASIVE BLADDER CANCER: COMBINATION OF EN- BLOC RESECTION BLADDER TUMOR AND INTRAVESICAL GEMCITABINE : A CASE REPORT
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Abstract
Bladder cancer ranks 11th in incidence and 13th in mortality in both sexes, of which 75-85% is non-muscle invasice bladder cancer (NIMBC). En-bloc resection of bladder tumor (ERBT) in the treatment of bladder cancer without muscle invasion has many advantages such as satisfactory pathology, low tumor survival rate, the recurrence rate is lower than standard endoscopic resertion (Transurethral resection of bladder tumor). Gemcitabine intravessical pump after surgery is a safe therapy to reduce the risk of recurrence. In this article, we report the case of an 84 year old male patient, admitted to the hospital with symtoms of hematuria and dysuria. The patient then underwent endoscopy to enblock the bladder tumor combined with intravesical gemcitabine, followed up at the 9 month with no sign of recurrence.
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Keywords
Enblock, ERBT, Bladder tumor, gemcitabine
References
2. M. Babjuk et al (2020), Non- muscle invasive Bladder cancer (TaT1 and CIS), EAU Guideline, pp. 22-28.
3. Team Edittorial (2021), "BCG or Gemcitabine for Bladder Cancer: When Should They Be Used?", Bladdercancernet.
4. Jun- Lin Lu et al (2020), "Efficacy of intravesical therapies on the prevention of recurrence and progression of non‐muscle‐invasive bladder cancer: A systematic review and network meta‐analysis", Cancer medicine, 9 (21) pp. 7800-7809.
5. Makito Miyake et al (2021), "Fluorescent cystoscopy-assisted en bloc transurethral resection versus conventional transurethral resection in patients with non-muscle invasive bladder cancer: study protocol of a prospective, open-label, randomized control trial (the FLEBER study)", Biomedcentral, pp 136 .
6. Massimiliano Creta et al (2022), "En-bloc Laser Resection of Bladder Tumors: Where Are We Now?", Journal of Clinical Medicine, 11(12) pp. 3463.
7. Rodolfo Hurle et al (2020), "Intravesical gemcitabine as bladder‐preserving treatment for BCG unresponsive non‐muscle‐invasive bladder cancer. Results from a single‐arm, open‐label study", BJUJ Compass, 1(4) pp. 126-132.
8. Slawomir Poletajew et al (2021), "En-bloc resection of urinary bladder tumour – a prospective controlled multicentre observational study", Video surgery and other miniinvasive techniques, 16(1) pp. 145-150.