RESULTS OF CONTROL OF BLOOD ACID URIC LEVELS BY FEBUXOSTAT IN PATIENTS WITH PRIMARY HYPERTENSION
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Abstract
Objective: Evaluation of the results of blood uric acid control by febuxostat in patients with primary hypertension. Subjects and methods: A cross-sectional descriptive study on 32 patients with hyperuricemia in primary hypertensive patients at Can Tho University of Medicine and Pharmacy Hospital in 2020 and 2021. Results: After 8 weeks of treatment with febuxostat 40mg, blood uric acid levels decreased from 528.5 mol/L before treatment to 302.5 mol/L. After 8 weeks of treatment, whether with a dose of 40mg or 80mg of febuxostat, there was a statistically significant reduction in blood acid uric and the rate of reaching the treatment goal increased from 67.6% at week 4 to 97.1% at week 8 (p=0.002). Conclusion: Febuxostat helps control uric acid levels in primary hypertensive patients with hyperuricemia.
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Keywords
hypertension, febuxostat, blood uric acid
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