KHẢO SÁT CHỨC NĂNG TUYẾN GIÁP SAU PHẪU THUẬT CẮT BÁN PHẦN TUYẾN GIÁP

Abstract

Research objectives: 1. To survey thyroid function after hemithyroidectomy. 2. To determinethe some factors that involved in development of hypothyroidism after hemithyroidectomy. Research subjects: Patients who received hemithyroidectomy follow - up examination between February 2022 and September 2022 in Hanoi Medical University Hospital was conducted. Thyroid specimens were examined for pathological diagnosis and thyroid function and thyroperoxidase antibody serum was evaluated. Method: Cross-sectional description. Results: 199 patients included in the study, 87% were women, mean age: 44,1 ± 12,53 (17-91). All had normal preoperative thyroid function. 1,5% patients pressented subclinical hypothyroidism; 69,35% patients remained euthyroid; 29,15% patients developed hypothyroidism (20,1% overt or symptomatic hypothyroidism and 9,04% subclinical hypothyroidism) with an average follow-up time of 16,59 ± 14,77 (2-86) months. The mean levothyroxine supplement dose was 0,91 ± 0,4 microg/kg per day. Preoperative high thyroid-stimulating hormone (TSH) level (1,55 ± 0,81 vs 2,87 ± 0,85; P: 0,05); thyroperoxidase antibody serum levels (25,58 ± 44,42 vs 73,82 ±  124,97; P < 0,05); and thyroid remnant volume (10,02 ± 4,41 vs 7,31 ±  4,19; p < 0,05) were significantly associated with postoperative hypothyroidism. Age, gender, follow-up time, preoperative free thyroxine, preoperative diagnosis, surgical methods, surgical complications and pathological diagnosis were not significant risk factors for hypothyroidism. Conclusion: After hemithyroidectomy, the prevalence of hyperthyroidism, euthyroidism and hypothyroidism were 1,5%, 69,35% and 29,15%, respectively. Preoperative high thyroid-stimulating hormone (TSH) level; thyroperoxidase antibody (Anti TPO) serum levels; and thyroid remnant volume were significantly associated with postoperative hypothyroidism.