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Date Published: 19/02/2023
Abstract Views: 231
Views PDF: 186
DOI: https://doi.org/10.51298/vmj.v522i2.4333
Issue
Vol. 522 No. 2 (2023)
Section
Các bài báo
How to Cite
Trần , T. N. L. ., & Nguyễn, T. H. M. . (2023). EFFICIENCY OF PLATELET-RICH FIBRIN IN PATIENTS WITH STAGE III PERIODONTITIS. Vietnam Medical Journal, 522(2). https://doi.org/10.51298/vmj.v522i2.4333

EFFICIENCY OF PLATELET-RICH FIBRIN IN PATIENTS WITH STAGE III PERIODONTITIS

Thị Nga Liên Trần 1,, Thị Hồng Minh Nguyễn1
1 National Hospital of Odonto-Stomatology, Hanoi

Main Article Content

Abstract

Objectives: The aim of the present clinical study was to determine the additive effects of PRF in the treatment of stage III periodontitis. Methods: Forty teeth in twenty patients were randomly assigned to PRF with open flap deridement group (experimental group) or open flap deridement group (control group). Clinical parameters and x ray included gingival index(GI) pocket depth (PD), clinical attachment loss (CAL), infrabony defect depth (IBD), bone fill (BF) were evaluated at baseline, 3-month, and at a 6-month evaluation. Wound healing index (WWHI) were evaluated at two weeks after surgery. Results: After 6-months surgical, result in a significant decrease in probing pocket depth 2,4±0,7 mm in group PRF+OFD compared with the control 1,5±0,6 mm ; clinical attachment level 2,6±0,8 mm in group PRF+OFD, 1,5±0,6 mm in group OFD;  infrabony defect depth 1,7±0,4 mm in group PRF+OFD, 0,6±0,6 mm in group OFD and increase percentage in bone fill 35,7%±9,7% in group PRF+OFD, 16,5%±18,0 % in group OFD. Wound healing index were evaluated at two weeks after surgery: good wound healing 95% in group PRF+OFD compared with the control 65%. Conclusions: These findings indicate that a combination of PRF and open flap  deridement is more effective than open flap deridement alone for the treatment of  stage III periodontitis.

Article Details

Keywords

fibrin-rich platelet, periodontal

References

1. Deodhar AK, Rana RE. Surgical physiology of wound healing: a review. J Postgard Med. 1997: 52-56.
2. Giannobile WV. Periodontal tissue engineering by growth factors, Bone. 1996: 23S-37S
3. Choukroun J, et al. PRF: an opportunity in perio implantology. Implantodontie. 2000:55-62.
4. Thorat M, et al. Clinical effects of autologous platelet rich fibrin in the treatment of intrabony defects: a controlled clinical trial, J Clin Periodontol, 2011:925-932.
5. Sharma A, Pradeep RA. Treatment of 3 – wall intrabony defects in patients with chronic periodontitis with autologous platelet rich fibrin: a randomized controlled clinical trial. J Periodotol. 2011;82(12):1705-1712. 6759.
6. Huang L.H, et al (2005). The effects of platelet rich plasma on the coronally advanced flap root coverage procedure: a pilot human trial, Journal of Periodontology. 2005: , pp. 1768-1777.
7. Cardaropoli G, Leonhardt AS. Enamel matrix proteins in the treatment of deep intrabony defects, Journal of Periodontology. 2002: 501-504.
8. Himanshu Ajwani, et al (2015). Comparative Evaluation of platelet- rich fibrin biomaterial and open flap debridement in the treatment of two and three wall intrabony defects, J Int Oral Health., 2015:pp. 32-37.
9. N. Markou, E. Pepelassi, H. Vavouraki, et al. Treatment of periodontal endosseous defects with platelet-rich plasma alone or in combination with demineralized freeze-dried bone allograft: a comparative clinical trial . Journal of Periodontology, 80 (2009), pp. 1911-1.
10. Tunc Ilgenli et al. Demineralized freeze-dried bone allograft and platelet-rich plasma vs platelet-rich plasma alone in infrabony defects: a clinical and radiographic evaluation. Clinical Oral Investigations, 11 (2007), pp. 51-59.