IMAGING CHARACTERISTICS ON MULTI-SLICE COMPUTED TOMOGRAPHY OF PULMONARY LESIONS IN PATIENTS WITH POST-COVID-19

Văn Sang Nguyễn1,2,3,, Văn Kiên Nguyễn2, Danh Vĩnh Đào4, Phan Ninh Trần2,3,5, Ngọc Thạch Phạm 6
1 E hospital
2 Thai Nguyen University Of Medicine And Pharmacy
3 Medlatec hospital
4 Medlatec hospital\
5 Vietnam National Children's Hospital
6 Hanoi medical university

Main Article Content

Abstract

Purpose: To analyze imaging characteristics of lung injury on multi-slice computed tomography in patients with post-COVID-19 at Medlatec hospital in 2022. Material and methods: Cross-sectional description of 1436 cases of post-COVID-19 examination at Medlatec hospital from March 2022 to September 2022, with 128-slice computed tomography. Results: The study was perfomed on 1436 patients (61.1% male, 38.9% female),  with average age of 39.3 ± 14.9 years old. The pulmonary lesions seen on CT scan were interstitial thickening (32.2%), ground glass opacity (17.3%), consolidation (8.4%), crazy-paving pattern (1.1%), bronchiectasis (9.5%), alveolar dilatation (8.2%), pulmonary vessel focal dilation (0.8%), subpleural bands (6.8%), honeycombing (0.6%), reversible halo/halo sign (0.1%). The average CT score of patients in the study group was 1.33±2.31 points, and that of the group with pulmonary lesions was 2.69±7.16 points. The age threshold at risk for post-COVID-19 lung damage was 38.5 years with a sensitivity of 63.5% and a specificity of 74.9%. Conclusions: High-resolution multi-slice computed tomography should be performed in all patients with post-COVID-19 persistent symptoms. Common lesions seen on CT scan are interstitial thickening, ground glass opacity. There are also fibrotic-like changes suggestive of post-COVID-19 pulmonary fibrosis.

Article Details

References

1. George PM, Patterson CM, Reed AK, Thillai M. Lung transplantation for idiopathic pulmonary fibrosis. Lancet Respir. Med. 2019; 7:271–282.
2. NIHR. Living with Covid19 – Second review. 2021. Available online at https://evidence.nihr.ac.uk/themedreview/living-with-covid19-second-review/.
3. Carfì A, Bernabei R, Landi F; Gemelli Against COVID-19 Post-Acute Care Study Group. Persistent symptoms in patients after acute COVID-19. JAMA. 2020;324(6):603-605
4. Solomon JJ, Heyman B, Ko JP, Condos R, Lynch DA. CT of Post-Acute Lung Complications of COVID-19. Radiology. 2021; 301:E383–E395.
5. Vijayakumar B, Tonkin J, Devaraj A, Philip KEJ, Orton CM, Desai SR et al. CT Lung Abnormalities after COVID-19 at 3 Months and 1 Year after Hospital Discharge. Radiology. 2022; 303(2):444-454.
6. Chen Y, Ding C, Yu L, Guo W, Feng X, Yu L et al. One-year follow-up of chest CT findings in patients after SARS-CoV-2 infection. BMC Med. 2021; 19(1):191.
7. Wei J, Yang H, Lei P, Fan B, Qiu Y, Zeng B et al. Analysis of thin-section CT in patients with coronavirus disease (COVID-19) after hospital discharge. J Xray Sci Technol. 2020; 28(3):383-389.
8. Guler SA, Ebner L, Aubry-Beigelman C, Bridevaux PO, Brutsche M, Clarenbach C et al. Pulmonary function and radiological features 4 months after COVID-19: first results from the national prospective observational Swiss COVID-19 lung study. Eur Respir J. 2021; 57(4):2003690.
9. Han X, Fan Y, Alwalid O, Li N, Jia X, Yuan M et al. Six-month Follow-up Chest CT Findings after Severe COVID-19 Pneumonia. Radiology. 2021; 299(1):E177-E186.