ROLE OF INFERIOR VENA CAVA SONOGRAPHIC PARAMETES AS PREDICTORS OF FLUID RESPONSIVENESS IN SEPTIC SHOCK

Viết Hậu Nguyễn1,, Vạn Phước Đặng 2
1 University of Medicine and Pharmacy at Ho Chi Minh City hospital
2 Vietnam national university Ho Chi Minh city

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Abstract

Background: In patients with septic shock, assessing fluid responsiveness played a crucial role in hemodynamic support. Ultrasound IVC measurements have been proven to have many advantages in predicting fluid responsiveness. Method: Prospective observational study at emergency department at University medical center. Fluid challenge was performed according to surviving sepsis campaign 2016. A ≥15% increase in stroke volume after fluid challenge was considered as fluid responsiveness. Inferior vena cava sonographic diameters were measured before and after the fluid challenge. Results: 96 septic patients with a mean age of 66,5 ±13,5 were enrolled between 07/2020 and 12/2021, all of the patients were mechanically ventilated, 38 patients were considered as fluid responders (39,6%). The area under the ROC curve for IVC-CI was 0,91 (95% CI: 0.85-0.98). The best cutoff value was 40% (Se = 92,1%, Sp = 79,3%, PPV = 66%, NPV = 93%). Conclusion: Sonographic inferior vena cava variability could be used to predict fluid responsiveness in septic shock.

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References

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