CHARACTERISTICS OF PATIENTS WITH ANAPHYLAXIS REQUIRING EXTRACORPOREAL MEMBRANE OXYGENATION IN BACH MAI HOSPITAL

Anh Tuấn Nguyễn1,2,, Quốc Linh Nguyễn1,2
1 Hanoi medical university
2 Bach Mai hospital

Main Article Content

Abstract

Objectives: To review some clinical characteristics and treatment results of patients after anaphylaxis requiring cardiopulmonary intervention at Bach Mai Hospital. Subjects: 19 patients with anaphylaxis received extracorporeal membrane oxygenation at Bach Mai hospital from January 2017 to June 2020. Methods: retrospective cross-sectional description. Patients were clinically assessed at the time of admission and recorded survival and mortality at discharge. Quantitative variables are presented as mean and standard deviation; using parametric tests for normally distributed variables and non-parametric tests for non-normally distributed variables; The difference was statistically significant with p < 0.05. Qualitative variables are presented as percentage (%), the difference is statistically significant with p < 0.05. Results: The percentage of female patients accounted for 100%. The average APACHE II score was 20.9 ± 6.0, in which the death group (25.2 ± 4.8) was higher than the survival group (18.9 ± 5.6) with p<0.05. Troponin T concentration at the time of admission had a median value of 1810 ng/ml (4.28 - 10000), the mortality group was higher than the survival group with p = 0.019. 94.7% had onset with cardiovascular signs, 79% of patients with anaphylaxis grade III or higher. Conclusions: Anaphylaxis patients requiring extracorporeal membrane oxygenation mainly had cardiovascular manifestations at the onset, mostly grade III and IV of anaphylaxis. The group of patients who died had a statistically significant higher APACHE II score and Troponin T concentration at the time of admission.

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References

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