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Date Published: 24/02/2023
Abstract Views: 494
Views PDF: 270
DOI: https://doi.org/10.51298/vmj.v523i1.4422
Issue
Vol. 523 No. 1 (2023)
Section
Các bài báo
How to Cite
Lê, T. L. ., & Thiều, T. T. M. (2023). RISK FACTORS OF METASTATIC LYMPH NODES IN PAPILLARY THYROID MICROCARCINOMA. Vietnam Medical Journal, 523(1). https://doi.org/10.51298/vmj.v523i1.4422

RISK FACTORS OF METASTATIC LYMPH NODES IN PAPILLARY THYROID MICROCARCINOMA

Tuấn Linh Lê1,2, Thị Trà My Thiều1,
1 Hanoi medical university hospital
2 Hanoi medical university

Main Article Content

Abstract

Objective: Papillary thyroid microcarcinoma (PTMC) is a variant of papillary thyroid carcinoma that measures less than 10mm on the largest diameter. There are some worse prognostic factors related to lymph node metastases. The aim of this study is to analyze the factors associated with PTMC with metastatic lymph nodes. Methods: We included 127 patients who diagnosed papillary microcarcinoma and undergone partial or total thyroidectomy at Ha Noi Medical University Hospital (from October 2020 to August 2022). Chi-Square and Fisher’s Exact Test were used to analyzed. The statistical significance was set at p < 0.05. Results: There were association between lymph node metastasis and multifocal cancer, bilateral cancer, capsular invasion (p<0.05). Lymph node metastasis was associated with both small PTMC (5/36 cases) and large PTMC (31/36 cases). Conclusions: For PTMC, multifocal, bilateral cancer and capsular invasion are associated with the high risk of lymph node metastasis.

Article Details

Keywords

Papillary thyroid microcarcinoma, risk factor, lymph node metastasis

References

1. Mercante G, Frasoldati A, Pedroni C, et al. Prognostic factors affecting neck lymph node recurrence and distant metastasis in papillary microcarcinoma of the thyroid: results of a study in 445 patients. Thyroid. 2009;19:707–16.
2. Roti E, Degli Uberti EC, Bondanelli M, et al. Thyroid papillary microcarcinoma: a descriptive and meta-analysis study. Eur J Endocrinol. 2008;159:659–73.
3. Haugen E, Alexander E, Bible K, et al. American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Differentiated Thyroid Cancer. Thyroid. 2015;26(1):1–133.
4. Davies L, Welch HG. Current thyroid cancer trends in the United States. JAMA Otolaryngol Head Neck Surg. 2014;140(4):317–322..
5. Bernet V. Approach to the patient with incidental papillary microcarcinoma. J Clin Endocrinol Metab. 2010;95(8):3586–3592.
6. Krzysztof K, Dorota D, Beata W, et al. Which papillary thyroid microcarcinoma should be treated as ‘true cancer’ and which as ‘precancer’?. World Journal of Surgical Oncology 2019; 17(1).
7. Ruiz Pardo J, Ríos A, Rodríguez JM, et al. Risk Factors of Metastatic Lymph Nodes in Papillary Thyroid Microcarcinoma. Cirugía Española (English Edition). 2020;98(4):219-225.