SO SÁNH PHƯƠNG PHÁP SIÊU ÂM ĐÁNH DẤU MÔ CƠ TIM Ở BN TRƯỚC VÀ SAU CẤY CRT VỚI CÁC THÔNG SỐ SIÊU ÂM TIM KHÁC

Abstract

Objectives: We compare the parameters measured by tissue Doppler echocardiography in patients before and after cardiac resynchronization therapy (CRT) implantation with several 2D-echocardiographic parameters. Methods: Data were prospectively collected from 33 patients with severe heart failure (left ventricular ejection fraction ≤ 35%), who were indicated for CRT in Vietnam National Heart Institute - Bach Mai Hospital. Echocardiography was performed before and at 3-month follow-up after CRT implantation. Results: The mean age was 60 years old and the early responder’s rates in 3-month follow-up were 30.3% of patients (LVEF increased ≥ 10%). In the group of early responders, mean QRS duration before the procedure and after 3-month follow-up were 133±6.3 ms and 111.5±4.7 ms, respectively. And in the nonresponder group, mean QRS duration before implantation was 134.3±4.1 ms and at 3 month after implantation was 112.0 ±4.2 ms. Patients, who responded early to CRT, had a greater reduction in Vs compared with the nonresponder group (25.3% vs 13.15%). The parameters on tissue Doppler echocardiography: E/A; E/e' decreased, and e'; a'; s' increased in all patients who underwent CRT implantation, and there was no difference between the early responder and nonresponder group (p>0.05). There was no correlation between the parameters derived from tissue Doppler echocardiography and the improvement of LVEF. Conclusions: The early responders’ rates to CRT within the first 3-month follow-up was 30.3%. The parameters derived from tissue Doppler echocardiography included E/A; E/E'; e’; a';s' was improved significantly before and 3 months after CRT implantation. However, there was no difference between the early responder and nonresponder group.