Article Sidebar

PDF
Date Published: 24/02/2023
Abstract Views: 153
Views PDF: 257
DOI: https://doi.org/10.51298/vmj.v523i1.4452
Issue
Vol. 523 No. 1 (2023)
Section
Các bài báo
How to Cite
Đặng, P. T., Trần , T. L. ., Dương, Đức H., & Nguyễn, D. T. . (2023). THE ROLE OF ULTRASOUND-GUIDED CORE NEEDLE BIOPSY IN INVASIVE CHARACTERISTICS DIAGNOSIS OF BREAST CANCER. Vietnam Medical Journal, 523(1). https://doi.org/10.51298/vmj.v523i1.4452

THE ROLE OF ULTRASOUND-GUIDED CORE NEEDLE BIOPSY IN INVASIVE CHARACTERISTICS DIAGNOSIS OF BREAST CANCER

Phước Triều Đặng1, Thị Linh Trần 1, Đức Hữu Dương1,, Duy Thái Nguyễn1
1 National cancer hospital

Main Article Content

Abstract

Objectives: To evaluate the value of ultrasound-guided core needle biopsy in diagnosing breast cancer histology in comparison with postoperative results. Subjects and Methods: A retrospective study was conducted at the National Cancer Hospital from June 2021 to June 2022, on 55 breast cancer patients diagnosed by ultrasound-guided core needle biopsy and operated on. Describe the characteristics of lesions on ultrasound, mammography, and factors in the biopsy process. Histological diagnosis on biopsy - operative tissue and related factors were analyzed. Results: The mean tumor size was 21.9mm. Ductal carcinoma was the most common histological type, accounting for 76.4%. The accuracy of histological diagnosis on ultrasound-guided core needle biopsy tissue was 74.5%. In the diagnosis of invasive breast cancer, core needle biopsy showed sensitivity, specificity, and accuracy of 87%, 100%, and 87.3%, respectively. The positive predictive value and the negative predictive value were 100% and 12.5%. Conclusion: Ultrasound-guided core needle biopsy is a valuable method in histological diagnosis, as well as the diagnosis of invasive breast cancer. However, in the diagnosis of breast cancer in situ, core needle biopsy still has many limitations, requiring an increase in sample size or the number of specimens to improve diagnostic capacity.

Article Details

Keywords

Breast cancer, Histology subtype diagnosis, invasive characteristics, core needle biopsy

References

1. Sung H, Ferlay J, Siegel RL, et al (2021). Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA Cancer J Clin, 71(3):209-249.
2. Gradishar WJ, Anderson BO, Balassanian R, et al (2018). Breast Cancer, Version 4.2017, NCCN Clinical Practice Guidelines in Oncology. J Natl Compr Canc Netw, 16(3):310-320.
3. Ough M, Velasco J, Hieken TJ (2011). A comparative analysis of core needle biopsy and final excision for breast cancer: histology and marker expression. Am J Surg, 201(5):692-4.
4. Brennan ME, Turner RM, Ciatto S, et al (2011). Ductal carcinoma in situ at core-needle biopsy: meta-analysis of underestimation and predictors of invasive breast cancer. Radiology, 260(1):119-28.
5. Park I, Kim J, Kim M, et al (2013). Comparison of the characteristics of medullary breast carcinoma and invasive ductal carcinoma. J Breast Cancer, 16(4):417-25.
6. Ozdemir A, Voyvoda NK, Gultekin S, Tuncbilek I, Dursun A, Yamac D (2007). Can core biopsy be used instead of surgical biopsy in the diagnosis and prognostic factor analysis of breast carcinoma? Clin Breast Cancer, 7(10):791-5.
7. Kerlikowske K (2010). Epidemiology of ductal carcinoma in situ. J Natl Cancer Inst Monogr, 2010(41):139-41.
8. Thomas M, Kelly ED, Abraham J, Kruse M (2019). Invasive lobular breast cancer: A review of pathogenesis, diagnosis, management, and future directions of early stage disease. Semin Oncol, 46(2):121-132.
9. Badoual C, Maruani A, Ghorra C, Lebas P, Avigdor S, Michenet P (2005). Pathological prognostic factors of invasive breast carcinoma in ultrasound-guided large core biopsies-correlation with subsequent surgical excisions. Breast, 14(1):22-7.
10. Harris GC, Denley HE, Pinder SE, et al (2003). Correlation of histologic prognostic factors in core biopsies and therapeutic excisions of invasive breast carcinoma. Am J Surg Pathol, 27(1):11-5.