KHẢO SÁT TÌNH HÌNH SỬ DỤNG KHÁNG SINH TRONG ĐIỀU TRỊ NHIỄM TRÙNG ĐƯỜNG TIẾT NIỆU TẠI BỆNH VIỆN ĐA KHOA THỐNG NHẤT ĐỒNG NAI

Abstract

Introduction: This study was designed to determine types and resistance rates of pathogens that caused Urinary tract infections (UTIs) and treatment results at Thong Nhat general Dong Nai hospital. Methods: A descriptive cross-sectional study was conducted on 171 medical records diagnosed with UTIs from January 2020 to December 2020 at Urology Department at Thong Nhat general Dong Nai hospital. Results: The age of the study population was (51.7 ± 17.8), 52% were female, in the total  of research samples there are 113 patients (66.1%) with at least 1 comorbidity, the most common comorbidities were hypertension diseases (18.7%), complicating factors for urinary tract infections (urinary structural abnormalities accounted for 62.6%), 57.9% were patients sampled for antibiogram, ratio positive was 48.5%, there are 34 cases identifying 1 bacteria and 2 cases identifying 2 bacteria, strains (73.7%) of gram-negative, of which Escherichia coli 39.5% was the most common bacteria, Proteus mirabilis 7.9%, Klebsiella pneumonia 7.9%, Pseudomonas aeruginosa 7.9%. Research results these bacteria have high resistance antibiotics: Escherichia coli resistant to 100% of cefazolin, cefotaxime, cefotetan and cefepime while other resistant antibiotics also have a resistance rate of over 50% of ampicillin, ceftriaxone, ceftazidime, ciprofloxacin. The results of diagnostic treatment decreased-hospital discharge accounted for the majority. Conclusion: The cause of UTIs was mainly due to Gram-negative organisms: Escherichia coli, Proteus mirabilis, Klebsiella pneumonia, Pseudomonas aeruginosa... These bacteria have high resistance antibiotics cefazolin, cefotaxime, ampicillin, ceftriaxone. Antibiotic resistance of bacteria is increasing in general and especially in the treatment of UTI in particular. Therefore, the regular provision antibiotic resistance of bacteria is necessary for doctors in treatment. Most of patients were discharged with improvement in symptoms.