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Date Published: 07/03/2023
Abstract Views: 319
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DOI: https://doi.org/10.51298/vmj.v523i2.4520
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Vol. 523 No. 2 (2023)
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Các bài báo
How to Cite
Nguyễn, H. H. Q., Nguyễn, A. T., & Nguyễn, H. Q. (2023). THE PROGNOSTIC VALUE OF EXTRAVASCULAR LUNG WATER INDEX IN CRITICALLY ILL SEPTIC SHOCK PATIENTS. Vietnam Medical Journal, 523(2). https://doi.org/10.51298/vmj.v523i2.4520

THE PROGNOSTIC VALUE OF EXTRAVASCULAR LUNG WATER INDEX IN CRITICALLY ILL SEPTIC SHOCK PATIENTS

Hữu Hồng Quân Nguyễn1,, Anh Tuấn Nguyễn1,2, Hữu Quân Nguyễn1,2
1 Hanoi medical university
2 Bach Mai hospital

Main Article Content

Abstract

Objective: To investigate the prognostic value of extravascular lung water index (EVLWI) in critically ill patients with septic shock in intensive care unit (ICU). Design: observational study. Setting: The Emergency center of Bach Mai hospital. Patients: We evaluated 31 patients. Interventions: From October 1, 2021 to October 30, 2022 This study prospectively recruited patients with sepsis sock from a medical intensive care unit (ICU) at the Emergency center of Bach Mai hospital. In each patient, transpulmonary thermodilution was used to measure cardiovascular hemodynamics and EVLI for 3 days via an arterial catheter placed within 48 h of the patient meeting the criteria for sepsis sock. All data were analyzed. Measurements and Main Results: In total, 31 patients were studied. EVLWI acted as an predictor for in-hospital survival. Medical ICU patients with extremely septic sock and a high EVLI (<10 ml/kg) had lower in-hospital survival rate than those with a low EVLI (>10 ml/kg) (35.7% vs. 64.3%, respectively, p<0.05) Conclusions: This investigation suggested that EVLI was an predictor for in hospital survival in medical ICU patients with septic sock. A reduction of EVLWI at early treatment was associated with a better prognosis.

Article Details

Keywords

Extravascular lung water index; Septic sock; Medical ICU;Transpulmonary thermodilution; Survival

References

1. Chung, F.-T.; Lin, S.-M. Impact of Extravascular Lung Water Index on Outcomes of Severe Sepsis Patients in a Medical Intensive Care Unit. Respir. Med. 2008, 102 (7), 956–961.
2. Abraham, E.; Shoemaker, W. C.; Cheng, P. H. Cardiorespiratory Responses to Fluid Administration in Peritonitis. Crit. Care Med. 1984, 12 (8), 664–668.
3. Nguyễn Hữu Quân. Nghiên cứu hiệu quả huyết động với sự hỗ trợ của phương pháp PiCCO trong xử trí sốc nhiễm khuẩn. Luận án Tiến sĩ, Đại học Y Hà Nội, 2016.
4. Martin, G. S.; Eaton, S.; Mealer, M.; Moss, M. Extravascular Lung Water in Patients with Severe Sepsis: A Prospective Cohort Study. Crit. Care Lond. Engl. 2005, 9 (2), R74-82.
5. The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3) - PubMed. https:// pubmed.ncbi.nlm.nih.gov/26903338/ (accessed 2021-06-06).
6. Rhodes, A.; Evans, L. E.; Alhazzani. Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016. Crit. Care Med. 2017, 45 (3), 486–552.
7. Lu, Y.; Zhang, H.; Teng, F. Early Goal-Directed Therapy in Severe Sepsis and Septic Shock: A Meta-Analysis and Trial Sequential Analysis of Randomized Controlled Trials. J. Intensive Care Med. 2018, 33 (5), 296–309.