INVESTIGATION ON DRUG TREATMENT OF DYSLIPIDEMIA IN HOSPITALIZED PATIENTS WITH ACUTE CORONARY SYNDROMES AT BA RIA HOSPITAL

Vĩnh Nguyên Nguyễn1, Như Hồ Nguyễn1, Ngọc Khôi Nguyễn1,
1 University of Medicine and Pharmacy at Ho Chi Minh City

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Abstract

Objectives: This study was designed to investigate medications to treat dyslipidemia in patients hospitalizated due to acute coronary syndromes at Cardiology and Geriatric Department of Ba Ria hospital. Methods: A retrospective, cross-sectional study was carried on medical records of inpatients at the Cardiology and Geriatric Department who had been diagnosed with acute coronary syndrome from August 1st 2020 to July 31st 2021. Patterns of drug use at hospital admission and discharge were analyzed. The relationship between risk factors and length of hospital stay or outcome were determined. Results: Patients who were prescribed high-intensity statins at admission and at discharge were 62.5% and 64.5%, respectively. Majority of UA and NSTEMI were prescribed atorvastatin, while STEMI was prescribed rosuvastatin on admission, and at discharge, majority of all three types were prescibed atorvastatin. Patients with a history of statin use are able to decrease length of hospital stay, while low glomerular filtration rate and myocardial infarction with/without ST elevation are able to increase length of hospital stay. The use of statins on admission resulted in a 8-fold reduction in the rate of outcomes in patients (death, stroke, referral to hospital, new myocardial infarction, heart failure). Conclusion: Consideration should be given to prescribing high-intensity statins for patients with a diagnosis of acute coronary syndrome, lasting after discharge from the hospital. More high-level study designs such as prospective cohort studies are needed to clearly identify affecting factors to length of hospital stay and outcomes.

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