RESULTS OF GASTROINTESTINAL NON - HODGKIN LYMPHOMA TREATMENT

Thị Thu Hường Nguyễn1,, Thanh Huyền Vũ 2, Huyền Nga Đỗ3
1 Hanoi medical university
2 National cancer hospital
3 Hong Ngoc hospital

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Abstract

Treatment of gastrointestinal non-Hodgkin lymphoma depends on pathologic features, stage and gastrointestinal complications. A descriptive study was conducted on 87 patients with gastrointestinal non-Hodgkin lymphoma, treated at the Department of Hematologic oncology department, K Hospital from May 2019 to August 2022. Procedure of treatment: surgery (2.3%), anti Helicobacter pylori (3.4%), chemotherapy (57.5%), radiation therapy (1.1%), surgery and chemotherapy (35.6%). Complete response rate was 75.3%, partial response rate was 11.8%, progression disease rate was 12.9%. PFS at 1 year and 3 years were 85.4% and 80.9%, respectively. OS at 1 year and 3 years were 82.2% and 78.9%, respectively. The adversely factors affected on the 3 years overall survival: elevated ß2M (87.4% vs 69.1%, p=0.028), tumors in esophagus and multiple sites (0% and 65.6% vs 80.8% (stomach) and 89.1% (intestine), p=0.01), no complete response after treatment (35.4% vs 98%, p< 0.001). There was no difference OS between operation or non-operation

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