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Date Published: 17/03/2023
Abstract Views: 323
Views PDF: 157
DOI: https://doi.org/10.51298/vmj.v524i1A.4620
Issue
Vol. 524 No. 1A (2023)
Section
Các bài báo
How to Cite
Phạm , H. K. ., Dương, Q. H. ., Nguyễn, Q. D. ., Trần , T. H. T., & Vũ , V. K. . (2023). INVESTIGATE THE STATUS OF EBV INFECTION IN GASTRIC CANCER PATIENTS IN VIET NAM. Vietnam Medical Journal, 524(1A). https://doi.org/10.51298/vmj.v524i1A.4620

INVESTIGATE THE STATUS OF EBV INFECTION IN GASTRIC CANCER PATIENTS IN VIET NAM

Hồng Khánh Phạm 1,, Quang Huy Dương1, Quang Duật Nguyễn1, Thị Huyền Trang Trần 2, Văn Khiên Vũ 2
1 103 Military Hospital, Vietnam Military Medical Academy
2 108 Military Central Hospital

Main Article Content

Abstract

Background: Along with H. pylori, EBV is emerging as a risk factor for gastric cancer. Vietnam is a country with a high prevalence of EBV, but there are no studies on EBV infection in gastric cancer patients. This study aims to determine the status of EBV infection and the characteristics of EBV-positive gastric cancer. Subjects and methods: Cross-sectional study of 179 patients: gastric cancer (n = 89) and chronic gastritis (n = 90) with diagnosed by histopathology. EBV infection was determined by realtime-PCR. Results: The rate of EBV infection of this population was 133/179 (74.3%), of which the gastric cancer group was higher than the chronic gastritis group (80.9% versus 67.8%), the difference was statistically significant (p < 0.05). Gastric cancer has the highest prevalence of EBV infection in the young age group (under 45) and is common in the cardia and body (100% and 92.9%, respectively). Conclusion: EBV infection may increase the "risk" of gastric cancer in Vietnam. EBV-positive gastric cancer is more common at young age and the tumor location is in the upper part of the stomach.

Article Details

Keywords

EBV, gastric cancer, chronic gastritis

References

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