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Date Published: 17/03/2023
Abstract Views: 269
Views PDF: 121
DOI: https://doi.org/10.51298/vmj.v524i1A.4625
Issue
Vol. 524 No. 1A (2023)
Section
Các bài báo
How to Cite
Lê, T. Đức ., & Phạm , T. D. . (2023). SURVIVAL RESULTS AND ASSOCIATED FACTORS OF PACLITAXEL REGIMEN CHEMOTHERAPY IN RECURRENT OR METASTATIC BREAST CANCER. Vietnam Medical Journal, 524(1A). https://doi.org/10.51298/vmj.v524i1A.4625

SURVIVAL RESULTS AND ASSOCIATED FACTORS OF PACLITAXEL REGIMEN CHEMOTHERAPY IN RECURRENT OR METASTATIC BREAST CANCER

Thanh Đức Lê1,, Thị Dịu Phạm 2
1 National cancer hospital
2 Hai Duong Medical technical University

Main Article Content

Abstract

Objectives: Our study aimed to evaluated survival results and associated factors of paclitaxel regimen chemotherapy in recurrent or metastatic breast cancer. Patients and methods: Retrospective, descriptive study on 47 patients with recurrent or metastatic of breast cancer, who were treated with paclitaxel chemotherapy regimen at National Cancer Hospital from 01/2017 to 01/2022. Results: The mean age of patients was 53.8 years old. The most common metastatic lesions were bone, lung, lymph node (mediastinal lymph node, abdominal lymph node, contralateral supraclavicular node) and liver accounting for 55.3%, 34.0%, 27.7% and 27.7%, respectively. 31 patients received the first-line regimen, accounting for 66.0%, and 16 patients received the second-line regimen, accounting for 34.0%. Median progression-free survival was 7.0 months (95% CI: 5,7-8.3). Median overall survival was 17.0 months (95% CI: 13.4-20.6). Patients with visceral metastases or patients treated in second-line regimen had a worse prognosis than patients without visceral metastases or patients receiving the first-line regimen. Conclusion: Paclitaxel regimen chemotherapy is effective in high survival time for recurrent or metastatic breast cancer with a median progression-free survival of 7.0 months and overall survival of 17.0 months.

Article Details

Keywords

metastatic breast cancer, paclitaxel, survival time.

References

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