ĐẶC ĐIÊM LÂM SÀNG, CẬN LÂM SÀNG CỦA BỆNH NHÂN UNG THƯ TỤY GIAI ĐOẠN TIẾN TRIỂN, DI CĂN TẠI BỆNH VIỆN K

Abstract

Objectives: Clinical and subclinical characteristics of patients with advanced and metastatic pancreatic cancer at K hospital. Patients and methods: Retrospective descriptive study of 170 patients were diagnosed locally advanced or metastatic pancreatic adenocarcinoma at K hospital. Results: The mean age was 49.2 years. The male/female ratio was 1.3/1. The proportion of patients with a history of smoking, alcohol, and diabetes were 42.4%, 44.1%, and 25.9%, respectively. Patients admitted to the hospital mainly because of abdominal pain accounted for 80.0%. There were 88 (51.8%) patients with pancreatic head cancer, 82 (48.2%) patients with tumors in the tail and body of the pancreas. Pancreatic ductal adenocarcinoma accounted for the majority (86.4%), other types accounted for a low percentage (13.6%). The rate of abdominal lymph nodes was 62.4%, of which 75(44.1%) patients had N1 nodes and 31(18.2%) patients had N2 nodes. The rate of tumor stage T2, T3 and T4 were 15.9%, 31.8% and 52.4%, respectively. Patients with distant metastases accounted for 62.9%. At the time of diagnosis, 78.7% of patients had elevated CA19.9 levels, 44.7% of patients had elevated CEA levels. In which 42.1% of patients had CA19.9 increased over 500 U/mL. Conclusion: Advanced or metastatic pancreatic cancer has a high rate of liver and peritoneal metastases, while lung and bone metastases are less common.