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Date Published: 17/03/2023
Abstract Views: 622
Views PDF: 237
DOI: https://doi.org/10.51298/vmj.v524i1A.4675
Issue
Vol. 524 No. 1A (2023)
Section
Các bài báo
How to Cite
Nguyễn, A. T. ., & Nguyễn, Q. L. . (2023). USE OF ACTIVATED CLOTTING TIME (ACT) TO ADJUST UNFRACTIONATED HEPARIN DOSE IN EXTRACORPOREAL MEMBRANE OXYGENATION. Vietnam Medical Journal, 524(1A). https://doi.org/10.51298/vmj.v524i1A.4675

USE OF ACTIVATED CLOTTING TIME (ACT) TO ADJUST UNFRACTIONATED HEPARIN DOSE IN EXTRACORPOREAL MEMBRANE OXYGENATION

Anh Tuấn Nguyễn1,2,, Quốc Linh Nguyễn1
1 Hanoi medical university
2 Bach Mai hospital

Main Article Content

Abstract

Objective: To evaluate the value of bedside ACT test in adjusting the dose of Heparin in patients undergoing ECMO technique at Bach Mai hospital. Subjects and methods: 67 ECMO patients from September 2019 to September 2020 at the Intensive Care Unit of Bach Mai Hospital were adjusted Heparin dose by bedside ACT test. Research results: ACT test correlates poorly with dose of Heparin and aPTT with r 0.14 and 0.17 p < 0.05, respectively, ACT has a mean correlation with CT INTEM with r 0.44 and p < 0.05. Conclusion: ECMO patients with heparin dose adjusted by the ACT test had a high target rate. The ACT test is moderately correlated with the CT INTEM.

Article Details

Keywords

bedside ACT test, ECMO

References

1. Buck M. L. (2005). Control of Coagulation during Extracorporeal Membrane Oxygenation. J Pediatr Pharmacol Ther, 10 (1), 26-35.
2. Phạm Đăng Thuần. Nhận xét hiệu quả phác đồ chống đông bằng heparin trong kỹ thuật tim phổi nhân tạo tại giường, Luận văn thạc sĩ Y học 2016; Tạp chi Y Học Việt Nam, Hà Nội.
3. Bembea MM, Annich G, Rycus P, et al. Variability in anticoagulation management of patients on extracorporeal membrane oxygenation: an international survey. Pediatric critical care medicine: a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 2013;14:e77.
4. Atallah S, Liebl M, Fitousis K, et al. Evaluation of the activated clotting time and activated partial thromboplastin time for the monitoring of heparin in adult extracorporeal membrane oxygenation patients. Perfusion 2014;29:456–61. doi:10.1177/0267659114524264
5. Prakash S, Wiersema UF, Bihari S, et al. Discordance between ROTEM® clotting time and conventional tests during unfractionated heparin-based anticoagulation in intensive care patients on extracorporeal membrane oxygenation. Anaesth Intensive Care 2016;44:85–92. doi:10.1177/0310057X1604400113
6. Sangalli F, Patroniti N, Pesenti A. ECMO-extracorporeal life support in adults. Springer 2014.