ĐẶC ĐIỂM LÂM SÀNG, CẬN LÂM SÀNG CỦA BỆNH NHÂN NGỘ ĐỘC CẤP CÓ TOAN LACTIC

Abstract

Objective: to describe the clinical and subclinical characteristics of lactic acidosis in patients with acute poisoning. Subjects and methods: a prospective observational study on 127 acute poisoned patients with lactic acidosis treated at the Poison Control Center of Bach Mai hospital from July 2019 to July 2020. Results: average age of study subjects was 37.2±15.8 years old. Ratio male/female was 1.7/1. Common clinical symptoms were nausea and vomiting (61.4%), tachycardia (43.3%), headache (33.8%), consciousness disorder (32.2%), and hypotension (25.9%), respiratory failure (27.5%). Laboratory results indicated anemia (34.6%), leukocytosis (40.9%), kidney failure (14.1%), hyperglycemia  (29.1%) hyponatremia  (17,3%) and hypokalemia (26.8%). Lactic acidosis presented with mean blood pH of 7.30 ± 0.15 and 18.9% with severe metabolic acidosis.  Conclusion: Acute poisoned patients with lactic acidosis had complicated clinical symptoms and laboratory abnormalities. Early evaluate clinical and laboratory features therefore is necessary to treat and predict complications.