ĐẶC ĐIỂM MỘT SỐ YẾU TỐ NGUY CƠ LIÊN QUAN ĐẾN HOẠI TỬ VÔ KHUẨN CHỎM XƯƠNG ĐÙI Ở NGƯỜI LỚN

Abstract

Objective: To determine some risk factors related to aseptic necrosis of the femoral head in adults. Subjects and methods: A cross-sectional descriptive study on 245 patients with aseptic necrosis of the femoral head at Viet Duc, Bach Mai, E and Thai Nguyen National Hospitals from Jan 2017 to April 2022. Results: Alcohol, tobacco, dyslipidemia, steroid are risk factors for aseptic necrosis of the femoral head, accounting for 64,5%, 42,0%, 34,3% and 15,5%, respectively. In which, the common risk factors in men were alcohol, tobacco and gout/hyperuricemia accounting for 77,2%, 50,5% and 26,2% in women were obese/overweight (44,2%). The group of patients with two femoral head necrosis had higher rates of steroid use than the group of patients with one femoral head necrosis (p<0,01). 63.2% of patients received steroids with a total dose of more than 2000 mg/patient. The mean duration of alcohol use was 19.35 months, median alcohol consumption was 2000 mL/week in patients with one femoral head necrosis, lower than in patients with two femoral head necrosis (28.35 months, 2800 mL/week), p<0,001. Conclusion: Alcohol, tobacco, dyslipidemia and steroid were risk factors for aseptic necrosis of the femoral head. Alcohol, tobacco and gout/hyperuricemia were more common in male patients, and obesity/overweight was common in female patients. Patients who used steroids, drink alcohol for a long time, had higher rate of bilateral femoral head necrosis than unilateral femoral head necrosis.