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Date Published: 24/03/2023
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Views PDF: 161
DOI: https://doi.org/10.51298/vmj.v524i1B.4757
Issue
Vol. 524 No. 1B (2023)
Section
Các bài báo
How to Cite
Nguyễn, H. L., & Nguyễn, T. G. H. . (2023). THE CORRELATION OF STO2 WITH LACTATE, PSOFA SCORE IN PEDIATRIC SEPTIC SHOCK AT CITY CHILDREN’S HOSPITAL. Vietnam Medical Journal, 524(1B). https://doi.org/10.51298/vmj.v524i1B.4757

THE CORRELATION OF STO2 WITH LACTATE, PSOFA SCORE IN PEDIATRIC SEPTIC SHOCK AT CITY CHILDREN'S HOSPITAL

Huy Luân Nguyễn1,, Thị Gia Hạnh Nguyễn2
1 University of Medicine and Pharmacy at Ho Chi Minh City
2 THE CHILDREN’S HOSPITAL

Main Article Content

Abstract

Background: Microcirculatory dysfunction appears early in the pathophysiology of septic shock and correlates with the severity of organ failure as well as mortality in the ICU. Tissue oxygen saturation (StO2) measured by near-infrared spectroscopy (NIRS) is one of the indicators that can be used to assess tissue oxygenation. Objectives: To determine the correlation of StO2 with lactate, pSOFA score at the time of shock (T0), after 6 hours (T6), and after 24 hours (T24) of treatment. Subjects and methods: A longitudinal observational study, 35 pediatric patients with septic shock from 11/2021 to 9/2022 inpatient treatment at City Children's Hospital. Results: StO2 at after 6 hours treatment was slightly negatively correlated with lactate (r = -0.368; p = 0.030). StO2 was negatively correlated with pSOFA score at all time points of the survey. The negative correlation between StO2 and lactate, the pSOFA score did not change when controlling confounding factors. Conclusion: Monitoring StO2 in combination with other macrovascular and microcirculatory hemodynamic parameters helps to detect microcirculatory disorders. Monitoring of StO2 at the time of shock, after 6 hours of treatment has the potential to support the prognosis of patients with multi-organ dysfunction.

Article Details

Keywords

tissue oxygen saturation (StO2), near-infrared spectroscopy (NIRS), septic shock.

References

1. Al Tayar A, Abouelela A, Mohiuddeen K (2017). Can the cerebral regional oxygen saturation be a perfusion parameter in shock? Journal of critical care;38:164-167
2. Das BP, Sharma M, Bansal S, et al. (2020). Prognostic Value of Tissue Oxygen Monitoring and Regional Cerebral Oxygen Saturation Monitoring and Their Correlation in Neurological Patients with Sepsis: A Preliminary, Prospective, Observational Study. Journal of neurosurgical anesthesiology. ; 32(1):77-81.
3. Kusumastuti NP, Ontoseno T, Endaryanto A (2022). Renal Oxygen Saturation as an Early Indicator of Shock in Children. Open access emergency medicine : OAEM.;14:123-131.
4. Macdonald SPJ, Kinnear FB, Arendts G, et al. (2019). Near-infrared spectroscopy to predict organ failure and outcome in sepsis: the Assessing Risk in Sepsis using a Tissue Oxygen Saturation (ARISTOS) study;26(3):174-179.
5. Marinova R, Groudeva V, Krastev P (2022). Tissue Oxygenation Measurement in Patients with Sepsis Compared to the Lactate Levels and Hemodynamical Monitoring. Proceedings of the Bulgarian Academy of Sciences.;75(8):1202-1209.
6. Mesquida J, Espinal C, Gruartmoner G, et al. (2012). Prognostic implications of tissue oxygen saturation in human septic shock. Intensive care medicine;38(4):592-7.