COMPARISON OF ANTIHYPERTENSIVE PREVENTION BETWEEN CONTINUOUS INTRAVENOUS INFUSION OF NORADRENALINE WITH PHENYLEPHERIN IN SPINAL BLOCK FOR CESAREAN SECTION IN NATIONAL HOSPITAL OF OBSTETRICS AND GYNECOLOGY

Minh Hồng Bùi 1,, Đức Lam Nguyễn2, Đức Trung Đỗ 3
1 Phu Tho General Hospital
2 Hanoi medical university
3 National hospital of obstetrics and gynecology

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Abstract

Objective: To compare undesirable effects on mother and newborn of continuous intravenous infusion of noradrenaline with phenylepherine in spinal block for cesarean section. Subjects and research methods: Pregnant women with indications for cesarean section at the National Hospital of Obstetrics and Gynecology. Results: Mean age, mean height, mean weight in the study of the two groups were similar. The rate of reactive hypertension after drug use in two groups was: 2% in the noradrenaline group and 4%% in the phenylepherin group. Nausea, vomiting, itching accounted for a very low proportion (3.33% to 10.0%). Apgar scores at 1 and 5 minutes both show that the baby's condition was stable post-delivery. Conclusion: Using the method of continuous infusion of noradrenaline or phenylephrine to prevent hypotension after spinal anesthesia for cesarean section did not cause any serious adverse effects on the mother and no effect on the Apgar score of the infant, there was also no difference between the two study groups.

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References

1. Kinsella SM, et al. (2018). International consensus statement on the management of hypotension with vasopressors during caesarean section under spinal anaesthesia. Anaesthesia. 73(1): p. 71-92..
2. Ngan Kee WD, et al. (2015). Randomized double-blinded comparison of norepinephrine and phenylephrine for maintenance of blood pressure during spinal anesthesia for cesarean delivery. Anesthesiology. 122(4): p. 736-45.
3. Sầm Thị Quý (2017). Đánh giá hiệu quả của phenylephrin tiêm tĩnh mạch dự phòng tụt huyết áp trong gây tê tủy sống để mổ lấy thai, luận văn bác sĩ chuyên khoa cấp II, Trường Đại học Y Hà Nội.
4. Teoh WH and AT Sia (2009). Colloid preload versus coload for spinal anesthesia for cesarean delivery: the effects on maternal cardiac output. Anesth Analg. 108(5): p. 1592-8.
5. Trần Xuân Hưng (2016). Đánh Giá Hiệu Quả Dự Phòng Tụt Huyết Áp Của Ephedrin Tiêm Bắp Trước GTTS Để Mổ Lấy Thai. Luận văn BSCK2, Trường Đại Học Y Hà Nội.
6. Hasanin A, Amin S, Refaat S et al (2019). Norepinephrine versus phenylephrine infusion for prophylaxis against post-spinal anaesthesia hypotension during elective caesarean delivery: A randomised controlled trial. Anaesth Crit Care Pain Med. 38(6):601-607