NGHIÊN CỨU TÌNH TRẠNG HẠ ĐƯỜNG MÁU Ở TRẺ SƠ SINH BỆNH LÝ CÓ CÂN NẶNG THẤP

Abstract

Objective: to describe the proportion, clinical characteristics and to identify the risk factors associated with hypoglycemia in sick LBW neonates. Subjects and methods: A cross-sectional descriptive study with 80 sick LBW neonates admitted in NICU of Hue University of Medicine and Pharmacy Hospital, Hue, Viet Nam, from April 2019 to March 2021. Results: A total of 80 neonates was included in our analysis, 32.5% neonates had at least one episode of hypoglycemia. Hypoglycemia was also accounted for 48.3% in the small for gestational age (SGA) babies and 23.5% in the appropriate for gestational age (AGA). The common clinical symptoms of hypoglycemia were tachypnea, hypothermia, and lethargy. The early-onset sepsis and SGA were significantly associated with hypoglycemia in LBW neonates (p<0.05). Whereas, maternal morbidities (diabetes, pre-eclampsia or eclampsia); or gestational age, birth weight, perinatal asphyxia were not significantly related to hypoglycemia in LBW neonates. Conclusions: 32.5% of sick LBW neonates had hypoglycemia. The proportion of LBW neonates with hypoglycemia without clinical manifestations was 34.6%. The early-onset sepsis and SGA associated with an increased risk of hypoglycemia in LBW neonates.