NGHIÊN CỨU MỘT SỐ CHỈ SỐ HÌNH THÁI, CHỨC NĂNG TIM Ở BỆNH NHÂN ĐÁI THÁO ĐƯỜNG TÝP 2 CÓ THỪA CÂN HOẶC BÉO PHÌ

Abstract

Objectives: To evaluate some cardiac morphological and functional indicators and their relationship with some characteristics in type 2 diabetes patients with overweight or obesity. Subjects and methods: A descriptive, cross-sectional study and comparison among three groups: group of type 2 diabetes patients with overweight or obesity (study group); group of type 2 diabetes patients without overweight or obesity (disease-control), and healthy subjects (control group). Results: 266 participants were divided into three groups. Interventricular septum thickness, left ventricular posterior wall, relative wall thickness, left ventricular muscle mass, left ventricular mass index in the study group was found to be the greatest, followed by the disease-control, and then the control group (p < 0.05). Interventricular septum e'-wave, lateral wall e’-wave in the study group were lower compared to the control group (p < 0.05). The study group had lower lateral e’-wave than the disease-control (p < 0.05). The E/e’ ratio (interventricular septum, lateral wall, mean) was higher in the study group and disease-control (p < 0.05). In the study group, lateral wall e’-wave in hypertension patients or older adults > 60 years old was higher than in comparison to those ≤ 60 years old or normotensive subjects. The mean E/e’ ratio was higher in patients > 60 years of age (p < 0.05). Conclusion: Type 2 diabetes patients with overweight or obesity had pronounced manifestations of  heart wall thickening and diastolic heart failure than the control group (p < 0.05). Hypertensive patients in the study group or subjects > 60 years of age had higher diastolic heart failure symptoms than normotensive subjects, or those ≤ 60 years old (p < 0.05).