TREATMENT RESULTS OF STAGE IIIB- IV NON-SMALL CELL LUNG CANCER WITH PEMETREXED - CISPLATIN REGIMEN

Nguyễn Việt Hà, Nguyễn Tuyết Mai

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Abstract

Objects: Evaluating the initial treatment results and toxicity of regimen Pemetrexed and Cisplatin in lung cancer patients at stage IIIB and IV. Subjects and Methods: Uncontrolled clinical intervention on 56 lung cancer patients non-small cell at stage IIIB and IV. Results: After 6 cycles: partial response 22/56 (39,3%), stable disease 26/56 (46,4%), clinical benefits 85,7%. 06 patients drop leukocyte at level 3 and 4, accounted for 10.7% . Progresive Free Survival  6,1 ± 3,3month , Overall Survival   10,7 ± 4,1 month. Survival rates after 1 and 2 year were 42,4% and 17,5%. Conclusion: Regimen Pemetrexed – Cisplatin was well outcome and tolerated in non-small cell lung cancer patients at distant metastasis stage.

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