INVESTIGATION ON MICROBIOLOGY AND ANTIBIOTIC RESISTANCE OF SOME COMMON BACTERIA IN PATIENTS WITH SEVERE DEEP NECK INFECTIONS AT CHO RAY HOSPITAL FROM 2019-2022

Văn Công Ngô 1,, Minh Thịnh Trương 2
1 Cho Ray hospital
2 University of Medicine and Pharmacy at Ho Chi Minh City

Main Article Content

Abstract

Background: Effective empiric antimicrobial treatment is important in deep neck infections, especially in severe cases. Objective: To investigate the microbiology and antibiotic resistance of common bacteria in severe deep neck infections to assist in the selection of initial antibiotic therapy. Methods: We did a retrospectively and prospectively descriptive study in cases of severe deep neck infections treated at Cho Ray Hospital from 12/2019 to 7/2022 with culture and sensitivity tests. Results: We recorded 99 cases of severe deep neck infections that fulfilled the sampling criteria. The median age was 57,3 ± 13,3 years. Microorganisms were successfully isolated in 67 cases (67.7%). Streptococcus sp was the most common bacteria (43.4%), followed by Klebsiella pneumoniae (19.2%), Staphylococcus aureus (6.1%), and Escherichia coli (3.0%). Streptococcus sp was highly resistant to clindamycin (60.0%), tetracycline (54.6%), and macrolides (40–55.0%). Klebsiella pneumoniae was 100% resistant to ampicillin. There was increased antibiotic resistance of microorganisms isolated to Cephalosporins. Vancomycin, linezolid, and carbapenems showed 100% sensitivity against all microorganisms isolated. Conclusion: Vancomycin, linezolid and carbapenems should be considered for initial antibiotic therapy of severe deep neck infections.

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References

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