EVALUATING THE SURVIVAL OUTCOME OF PATIETNS DIAGNOSED OF P16-POSITIVE OROPHARYNGEAL CANCER AT NATIONAL CANCER HOSPITAL

Hùng Kiên Đỗ 1,, Thị Hậu Trần 2
1 K hospital
2 k hospital

Main Article Content

Abstract

Objective: Evaluating the survival outcomes and analyzing the prognostic factors of patients diagnosed of p16-positive oropharyngeal cancer at National Cancer Hospital from 09/2017 to 09/2022. Patients and method: Retrospective and prospective analysis of 33 patients with p16-positive oropharyngeal cancer were diagnosed and treated at National Cancer Hospital from 09/2017 to 09/2022. Results: The 3-year and 5-year overall survival (OS) rates were 78.2% and 76.1%, respectively. Patients with stages I-II had higher 5-year OS rate than patients with stages III-IV (86,2% vs 67.9%), there was a significant difference with p=0.044. Patients with ECOG 0-1 had higher 5-year OS rate than patients with ECOG 2-3 (82.3% vs 66.8%), there was a significant difference with p=0.043. Age, sex and histological grade did not influence the 5-year OS rate. Conclusion: P16-positive oropharyngeal squamous cell cancer patient have good prognosis with the 5-year OS rate of 76.1%. Disease stage and ECOG influenced overall survival.

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References

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