THE PREVALENCE AND RISK FACTORS RELATED TO SYMPTOM PERSISTENCE AFTER COVID-19 IN VIETNAMESE CHILDREN AT CHILDREN’S HOSPITAL 1

Nguyễn Thế Nguyên Phùng 1,2, Thanh Thức Trần 1,2,, Thanh Hùng Nguyễn2,3, Ngọc Quang Minh Ngô 2, Bích Y Linh Nguyễn1, Quốc Duy Đặng2, Minh Tuân Trần 1
1 University of Medicine and Pharmacy at Ho Chi Minh City
2 THE CHILDREN’S HOSPITAL 1
3 Vietnam National university Ho Chi Minh city

Main Article Content

Abstract

Introduction: The data on prolonged symptoms after COVID-19 and their impact on children is still limited. This study aims to describe the prevalence, and characteristics of persistent symptoms after COVID-19 and find out risk factors related to symptom persistence after COVID-19 in Vietnamese children. Methods: A descriptive prospective follow-up study was conducted from August to November 2021. We interviewed the patient’s caregivers at the time of one and two months after their discharge about the children’s health status and if there were still any symptoms related to COVID-19. The symptoms asked were based on WHO’s Global Clinical Data Platform 1 of COVID-19. Results: One hundred ninety-six hospitalized children with positive SARS-CoV-2 results, with a median age of 16.4 months, were included. Acute phase severity was recorded from mild to critical. At the time of discharge, 34.2% (67 children) still had at least 1 symptom. After 1 month and 2 months, this rate dropped to 15.8% and 9.7%, respectively. After 2 months, there were 19/196 cases with persistent symptoms, in which respiratory symptoms still accounted for the highest rate: cough (42.1%), wheezing (31.6%), and shortness of breath (10.5%). No factors were found to be related to the prolongation of symptoms after SARS-CoV-2 infection in children. Conclusions: The prevalence of persistent symptoms in COVID-19 children 2 months after discharge in the study was relatively low, and most of the symptoms were mild. Further studies are needed to fully understand the impact of long COVID in children, especially young children.

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References

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