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Date Published: 21/07/2021
Abstract Views: 301
Views PDF: 200
DOI: https://doi.org/10.51298/vmj.v501i2.485
Issue
Vol. 501 No. 2 (2021)
Section
Các bài báo
How to Cite
Thu Hương, D. ., Phạm Thảo Nguyên, H. ., Công Nhật Nam, H. ., Thu Thủy, N. ., & Văn Khoa, P. (2021). EVALUATE THE ANTIMICROBIAL EFFICACY OF 2% CHLORHEXIDINE SOLUTION ON NECROTIC PULP BY REAL – TIME PCR. Vietnam Medical Journal, 501(2). https://doi.org/10.51298/vmj.v501i2.485

EVALUATE THE ANTIMICROBIAL EFFICACY OF 2% CHLORHEXIDINE SOLUTION ON NECROTIC PULP BY REAL – TIME PCR

Dương Thu Hương, Huỳnh Phạm Thảo Nguyên, Huỳnh Công Nhật Nam, Nguyễn Thu Thủy, Phạm Văn Khoa

Main Article Content

Abstract

Objectives: To evaluate clinical antimicrobial efficacy of 2 % CHX solution on human root canals containing necrotic pulp tissue by real-time PCR. Materials and methods:Clinical trial study, evaluate the bacteria amount by real – time PCR on 32 root canals containing necrotic pulp before and after being irrigated with 2% CHX solution. Results:The amount of bacteria remained in root canals after treatment was significantly lower than the initial bacterial load (p<0.001). The amount of baseline bacteria was 1770x103 DU and after treatment was only 16.55x103 DU. Bacteria on the anterior teeth, premolar and molar teeth all decreased significantly after being treated with 2% CHX solution (p<0.05), there was no difference about the remaining bacteria after treatment in three teeth groups (p>0.05). The amount of bacteria in the necrotic pulp with and without exposing pulp chamber both decreased significantly after treatment with 2% CHX solution (p<0.001), the remaining bacteria in the exposing group was higher than the non-exposing group with statistically significant (p<0.05). Conclusion: 2% CHX solution is effective irrigating solution on necrotic pulp, including teeth had exposure and no exposure of pulp chamber.

Article Details

Keywords

Chlorhexidine, hypochlorite sodium, endodontic infection, real – time PCR

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