RESEARCH ON RELATIONSHIP BETWEEN PLASMA 25-HYDROXYVITAMIN D AND DIABETIC KIDNEY DISEASE IN TYPE 2 DIABETES PATIENTS

Lê Diệu Hiền Nguyễn1,, Thị Tuyết Ngô 1, Khánh Hải Phan 2, Trung Thế Lê2
1 DA NANG UNIVERSITY OF MEDICAL TECHNOLOGY AND PHARMACY
2 Da Nang hospital

Main Article Content

Abstract

Objective:  The study aimed to determine the prevalence of 25-Hydroxyvitamin D deficiency in the blood and analyze the relationship between 25-Hydroxyvitamin D and diabetic kidney disease in patients with type 2 diabetes. Subject and method: By cross-sectional method, 117 patients were diagnosed with type 2 diabetes at the Department of Nephrology – Endocrinology, Da Nang Hospital. Results: The rate of blood 25-Hydroxyvitamin D deficiency in patients with type 2 diabetes was 80,3%. The concentration of 25-Hydroxyvitamin D was moderately inversely correlated with the degree of albuminuria (r = -0,478; p = 0,004); 25-Hydroxyvitamin D concentration has a moderate positive correlation with glomerular filtration rate (r = 0,435; p < 0,05). An association was found between 25-Hydroxyvitamin D deficiency and diabetic kidney disease which 25-Hydroxyvitamin D deficiency group had a 2,83 times higher risk of diabetic kidney disease than the 25-Hydroxyvitamin D sufficiency group (OR = 2,83; 95%CI = 1,101-7,27; p = 0,031).

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References

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