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Date Published: 12/04/2023
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DOI: https://doi.org/10.51298/vmj.v525i1A.4936
Issue
Vol. 525 No. 1A (2023)
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How to Cite
Đỗ , H. K. ., & Nguyễn, T. N. H. . (2023). ASSESSING THE TREATMENT RESULTS OF DOUBLET PLATINUM-BASED CHEMOTHERAPY IN METASTATIC/RECURRENT SQUAMOUS CELL HEAD AND NECK CANCER. Vietnam Medical Journal, 525(1A). https://doi.org/10.51298/vmj.v525i1A.4936

ASSESSING THE TREATMENT RESULTS OF DOUBLET PLATINUM-BASED CHEMOTHERAPY IN METASTATIC/RECURRENT SQUAMOUS CELL HEAD AND NECK CANCER

Hùng Kiên Đỗ 1,, Thị Như Hoa Nguyễn1
1 k hospital

Main Article Content

Abstract

Objective: Assessing treatment responses of doublet platinum-based chemotherapy in patients with recurrent/metastatic squamous cell head and neck cancer at K Hospital. Patients and method: Retrospective and prospective analysis of 62 recurrent/metastatic squamous cell head and neck cancer patients treated with first-line doublet platinum-based chemotherapy at K Hospital from 12/2018 to 12/2022. Results: Majority of patients were male (77.4%) with age < 65 years old (69.4%). ECOG performance status 1 was observed in 59.7%. Metastatic stage at diagnosis was 75.8%. Lung metastasis was observed in 59.7%. Majority of patients received cisplatin-based regimens (60.9%). Partial response rate was seen in 27.4% and disease control rate was 59.7%. Cisplatin regimen was associated with higher overall response rate compared to carboplatin regimen. Conclusion: Doublet platinum-based chemotherapy for the treatment of recurrent/metastatic squamous cell head and neck cancer had improved clinical symptoms with a response rate of 27.4%.

Article Details

Keywords

squamous cell head and neck cancer, recurrent/metastatic stage, doublet platinum-based chemotherapy

References

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